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Author Shani, J.; Barak, S.; Levi, D.; Ram, M.; Schachner, E.R.; Schlesinger, T.; Robberecht, H.; Van Grieken, R.; Avrach, W.W.
Title Skin penetration of minerals in psoriatics and guinea-pigs bathing in hypertonic salt solutions Type A3 Journal article
Year (down) 1985 Publication Pharmacological research communications Abbreviated Journal
Volume 17 Issue 6 Pages 501-512
Keywords A3 Journal article; Pharmacology. Therapy; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract Penetration of electrolytes through the human skin was measured in healthy volunteers and in psoriatic patients after bathing in the Dead-Sea or in simulated bath-salt solutions. Significant increases in the levels of serum Br, Rb, Ca and Zn were noticed only in the psoriatic patients after daily bathing in the Dead-Sea for a 4-week regimen. Guinea-pigs bathed in simulated Dead-Sea bath-salt solutions containing radionuclides of Ca, Mg, K and Br. Traces of each radionuclide were detected in the blood and in some internal organs after 60 minutes of bathing. The radionuclides showed a physiological pattern in their organ distribution. Even though the whole investigation was carried out in hypertonic solutions, there is a definite penetration of salts through healthy (human and guinea-pigs) and damaged (psoriatic) epidermis. This finding suggests that improvement of the psoriatic condition after bathing in the Dead-Sea, may be partly attributed (in addition to ultraviolet irradiation) to the minerals' effect on the psoriatic skin.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date 2006-07-20
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-6989 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116755 Serial 8547
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Author Shani, J.; Livshitz, T.; Robberecht, H.; Van Grieken, R.; Rubinstein, N.; Even-Paz, Z.
Title Increased erythrocyte glutathione peroxidase activity in psoriatics consuming high-selenium drinking water at the dead-sea psoriasis treatment center Type A3 Journal article
Year (down) 1985 Publication Pharmacological research communications Abbreviated Journal
Volume 17 Issue 5 Pages 479-488
Keywords A3 Journal article; Pharmacology. Therapy; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract Erythrocyte selenium-dependent glutathione peroxidase activity was measured in psoriatic Danes, before and after their four-week balneological therapy at the Ein-Bokek International Psoriasis Treatment Center, on the Dead-Sea shore in Israel. The drinking water in Ein-Bokek was found to be rich in selenium, a trace element with anticarcinogenic properties and of great importance in human nutrition and health. The most reliable biological parameter for increase in selenium bioavailability is the erythrocytes' glutathione-peroxidase activity. As psoriasis is a proliferative skin disease, the activity of this enzyme was assayed in 35 psoriatic Danes and in 25 long-term local hotel workers, as well as in 34 volunteers drinking low-selenium water. The glutathione peroxidase activity in the psoriatic patients increased significantly during their four-week stay in Ein-Bokek. Erythrocyte glutathione peroxidase activity in the hotel workers was 50% higher than that in the healthy volunteers consuming low-selenium water. A possible role of selenium in psoriasis is suggested.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date 2004-10-04
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-6989 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116758 Serial 8076
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Author Shani, J.; Barak, S.; Ram, M.; Levi, D.; Pfeifer, Y.; Schlesinger, T.; Avrach, W.W.; Robberecht, H.; Van Grieken, R.
Title Serum bromine levels in psoriasis Type A1 Journal article
Year (down) 1982 Publication Pharmacology Abbreviated Journal
Volume 25 Issue 6 Pages 297-307
Keywords A1 Journal article; Pharmacology. Therapy; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract Serum bromine levels in psoriatic Danes increased 2- to 3-fold during a 4-week bathing course in the Dead Sea. This increase correlated well with the improvement in their clinical and psychic condition. Serum bromine levels in psoriatic Danes were somewhat lower than those in healthy subjects residing in Denmark, but the difference was not significant. Israelis working in the open air in the Dead Sea area (air bromine 20-fold higher than in Jerusalem) had higher bromine levels than psoriatic or healthy Israelis residing in Jerusalem or healthy Israelis working in air-conditioned rooms in the Dead Sea area (p < 0.05), but those levels were still within the normal range. As our animal experimentation indicates that the skin is a major target organ for 82Br, applied either by bathing or as an aerosol, we conclude that the higher bromine levels noticed in the psoriatic Danes after their 4-week stay at the Dead Sea may be equally due to their contact with the bromine-containing aerosol and the high bromine level of the Dead Sea waters.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos A1982PV13800001 Publication Date 2008-06-05
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-7012 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116653 Serial 8515
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Author Robberecht, H.; Van Grieken, R.; Shani, J.; Barak, S.
Title Evaluation of multi-element analysis of blood serum by energy-dispersive x-ray spectrometry Type A1 Journal article
Year (down) 1982 Publication Analytica chimica acta Abbreviated Journal
Volume 136 Issue Pages 285-292
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract Conventional energy-dispersive x-ray fluorescence is applied in the analysis of blood serum to give the concentrations of 710 elements simultaneously with minimal manipulation of the samples. Simple spotting onto a Mylar carrier of 250 μl of serum, doped with two internal standards, was chosen as the sample preparation step. Some 200 serum samples, analyzed in replicate (n = 26), were used to evaluate this procedure. The detection limits are 4 μg ml-1 for K and Ca, 0.50.2 μg ml-1 for Fe, Cu, Pb and Zn, and less than 0.1 μg ml-1 for Se, Rb and Sr. Well above these limits, the standard deviation is around 10%. Comparison with the results of other measurements on the same samples indicates an accuracy of that order. The simplicity and high throughput, and the possibility of automating the x.r.f. measurements, make the proposed procedure suitable for screening large numbers of sera.
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Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos A1982NL48600032 Publication Date 2002-07-25
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0003-2670; 1873-4324 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116440 Serial 7940
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Author Van Grieken, R.; Robberecht, H.; Shani, J.; Van Dyck, P.; Vos, L.
Title Energy-dispersive X-ray fluorescence for direct trace analysis of biomedical and environmental samples Type H3 Book chapter
Year (down) 1982 Publication Abbreviated Journal
Volume Issue Pages 159-178 T2 - X-ray fluorescence (XRF and PIXE) in
Keywords H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:117485 Serial 7904
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