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Author |
Shani, J.; Livshitz, T.; Robberecht, H.; Van Grieken, R.; Rubinstein, N.; Even-Paz, Z. |
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Title |
Increased erythrocyte glutathione peroxidase activity in psoriatics consuming high-selenium drinking water at the dead-sea psoriasis treatment center |
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A3 Journal article |
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Year  |
1985 |
Publication |
Pharmacological research communications |
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Volume |
17 |
Issue |
5 |
Pages |
479-488 |
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Keywords |
A3 Journal article; Pharmacology. Therapy; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Abstract |
Erythrocyte selenium-dependent glutathione peroxidase activity was measured in psoriatic Danes, before and after their four-week balneological therapy at the Ein-Bokek International Psoriasis Treatment Center, on the Dead-Sea shore in Israel. The drinking water in Ein-Bokek was found to be rich in selenium, a trace element with anticarcinogenic properties and of great importance in human nutrition and health. The most reliable biological parameter for increase in selenium bioavailability is the erythrocytes' glutathione-peroxidase activity. As psoriasis is a proliferative skin disease, the activity of this enzyme was assayed in 35 psoriatic Danes and in 25 long-term local hotel workers, as well as in 34 volunteers drinking low-selenium water. The glutathione peroxidase activity in the psoriatic patients increased significantly during their four-week stay in Ein-Bokek. Erythrocyte glutathione peroxidase activity in the hotel workers was 50% higher than that in the healthy volunteers consuming low-selenium water. A possible role of selenium in psoriasis is suggested. |
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Publication Date |
2004-10-04 |
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ISSN |
0031-6989 |
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UA library record |
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Open Access |
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Call Number |
UA @ admin @ c:irua:116758 |
Serial |
8076 |
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