Records |
Author |
Drăgan, A.-M.; Parrilla, M.; Feier, B.; Oprean, R.; Cristea, C.; De Wael, K. |
Title |
Analytical techniques for the detection of amphetamine-type substances in different matrices : a comprehensive review |
Type |
A1 Journal article |
Year |
2021 |
Publication |
Trac-Trends In Analytical Chemistry |
Abbreviated Journal |
Trac-Trend Anal Chem |
Volume |
145 |
Issue |
|
Pages |
116447 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Antwerp Electrochemical and Analytical Sciences Lab (A-Sense Lab) |
Abstract |
This current review focuses on contributions to amphetamine-type substances (ATS) analysis. This type of synthetic illicit drugs has been increasingly present worldwide reaching 5% of the market on illicit drugs in 2019. The increment of their production in many clandestine laboratories and easy distribution among society are two of the main concerns towards the battle against synthetic drugs. Therefore, the first part of this review details the classification and mechanism of action of ATS in the human body. Second, the pharmacological and toxicological effects of ATS on human health are described to motivate the need of early detection of ATS. Subsequently, the most used laboratory-based and portable methods are presented and critically discussed along the review. Finally, a careful discussion on the advantages and disadvantages of portable techniques employed on the field are addressed as potential tools for on-site ATS detection by law enforcement officers. |
Address |
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Corporate Author |
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Thesis |
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Publisher |
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Place of Publication |
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Editor |
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Language |
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Wos |
000723747000009 |
Publication Date |
2021-09-30 |
Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0165-9936; 1879-3142 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
8.442 |
Times cited |
|
Open Access |
OpenAccess |
Notes |
|
Approved |
Most recent IF: 8.442 |
Call Number |
UA @ admin @ c:irua:183268 |
Serial |
7460 |
Permanent link to this record |
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|
Author |
Kuczumov, A.; Vekemans, B.; Schalm, O.; Vincze, L.; Dorriné, W.; Gysels, K.; Van Grieken, R. |
Title |
Application of auxiliary signals in X-ray fluorescence and electron microprobe analysis for density evaluation |
Type |
A1 Journal article |
Year |
1999 |
Publication |
X-ray spectrometry |
Abbreviated Journal |
|
Volume |
28 |
Issue |
|
Pages |
282-291 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
|
Address |
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Corporate Author |
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Thesis |
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Publisher |
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Place of Publication |
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Editor |
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Language |
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Wos |
000081693400014 |
Publication Date |
2002-09-10 |
Series Editor |
|
Series Title |
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Abbreviated Series Title |
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Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0049-8246 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
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Times cited |
|
Open Access |
|
Notes |
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Approved |
no |
Call Number |
UA @ admin @ c:irua:27584 |
Serial |
7467 |
Permanent link to this record |
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|
|
Author |
Osán, J.; de Hoog, J.; Worobiec, A.; Ro, C.-U.; Oh, K.-Y.; Szalóki, I.; Van Grieken, R. |
Title |
Application of chemometric methods for classification of atmospheric particles based on thin-window electron probe microanalysis data |
Type |
A1 Journal article |
Year |
2001 |
Publication |
Analytica chimica acta |
Abbreviated Journal |
|
Volume |
446 |
Issue |
|
Pages |
211-222 |
Keywords |
A1 Journal article; Laboratory Experimental Medicine and Pediatrics (LEMP); AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
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Address |
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Corporate Author |
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Thesis |
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Publisher |
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Place of Publication |
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Editor |
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Language |
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Wos |
000172309400020 |
Publication Date |
|
Series Editor |
|
Series Title |
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Abbreviated Series Title |
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Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0003-2670; 1873-4324 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:36385 |
Serial |
7468 |
Permanent link to this record |
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|
Author |
Uzonyi, I.; Szöör, G.; Vekemans, B.; Vincze, L.; Rozsa, P.; Szabo, G.; Somogyi, A.; Adams, F.; Kiss, Á.Z. |
Title |
Application of combined micro-proton-induced X-ray emission and micro-synchrotron radiation X-ray fluorescence techniques for the characterization of impact materials around Barringer Meteor Crater |
Type |
A1 Journal article |
Year |
2004 |
Publication |
Spectrochimica acta: part B : atomic spectroscopy |
Abbreviated Journal |
|
Volume |
59 |
Issue |
|
Pages |
1717-1723 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
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Address |
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Corporate Author |
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Thesis |
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Publisher |
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Place of Publication |
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Editor |
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Language |
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Wos |
000224848000031 |
Publication Date |
2004-09-14 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0584-8547; 1873-3565 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:49638 |
Serial |
7469 |
Permanent link to this record |
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|
|
Author |
Spolnik, Z.; Bencs, L.; Worobiec, A.; Kontozova, V.; Van Grieken, R. |
Title |
Application of EDXRF and thin window EPMA for the investigation of the influence of hot air heating on the generation and deposition of particulate matter |
Type |
A1 Journal article |
Year |
2005 |
Publication |
Microchimica acta |
Abbreviated Journal |
|
Volume |
149 |
Issue |
|
Pages |
79-85 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Laboratory Experimental Medicine and Pediatrics (LEMP) |
Abstract |
|
Address |
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Corporate Author |
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Thesis |
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Publisher |
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Place of Publication |
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Editor |
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Language |
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Wos |
000226408200010 |
Publication Date |
2005-01-18 |
Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
|
ISBN |
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Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
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Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:51258 |
Serial |
7471 |
Permanent link to this record |
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|
|
Author |
Xhoffer, C.; Jacob, W.; Van Grieken, R. |
Title |
Application of electron energy loss spectroscopy to aerosols |
Type |
A1 Journal article |
Year |
1989 |
Publication |
Journal of aerosol science |
Abbreviated Journal |
|
Volume |
20 |
Issue |
8 |
Pages |
1617-1619 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
|
Address |
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Corporate Author |
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Thesis |
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Publisher |
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Place of Publication |
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Editor |
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Language |
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Wos |
A1989CN23100191 |
Publication Date |
2003-08-06 |
Series Editor |
|
Series Title |
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Abbreviated Series Title |
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Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0021-8502; 1879-1964 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:116820 |
Serial |
7472 |
Permanent link to this record |
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|
|
Author |
Szalóki, I.; Varga, K.; Van Grieken, R. |
Title |
Application of energy dispersive X-ray spectrometry for quantitative evaluation of sorption phenomena at solid-liquid interfaces |
Type |
A1 Journal article |
Year |
2000 |
Publication |
Spectrochimica acta: part B : atomic spectroscopy |
Abbreviated Journal |
|
Volume |
55 |
Issue |
|
Pages |
1031-1038 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
|
Address |
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Corporate Author |
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Thesis |
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Publisher |
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Place of Publication |
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Editor |
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Language |
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Wos |
000088353100032 |
Publication Date |
2002-07-25 |
Series Editor |
|
Series Title |
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Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0584-8547; 1873-3565 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:32124 |
Serial |
7473 |
Permanent link to this record |
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|
|
Author |
Kontozova-Deutsch, V.; Deutsch, F.; Godoi, R.H.M.; Spolnik, Z.; Wei, W.; Van Grieken, R. |
Title |
Application of EPMA and XRF for the investigation of particulate pollutants in the field of cultural heritage |
Type |
A1 Journal article |
Year |
2008 |
Publication |
Microchimica acta |
Abbreviated Journal |
|
Volume |
161 |
Issue |
3/4 |
Pages |
465-469 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
|
Address |
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Corporate Author |
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Thesis |
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Publisher |
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Place of Publication |
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Editor |
|
Language |
|
Wos |
000256175600029 |
Publication Date |
2008-01-30 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0026-3672; 1436-5073 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:68798 |
Serial |
7474 |
Permanent link to this record |
|
|
|
Author |
van Meel, K.; Fontàs, C.; Van Grieken, R.; Queralt, I.; Hidalgo, M.; Marguí, E. |
Title |
Application of high-energy polarised beam energy dispersive X-ray fluorescence spectrometry to cadmium determination in saline solutions |
Type |
A1 Journal article |
Year |
2008 |
Publication |
Journal of analytical atomic spectrometry |
Abbreviated Journal |
|
Volume |
23 |
Issue |
7 |
Pages |
1034-1037 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
|
Address |
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Corporate Author |
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Thesis |
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Publisher |
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Place of Publication |
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Editor |
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Language |
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Wos |
000257146000017 |
Publication Date |
2008-04-22 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
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Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0267-9477 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:69424 |
Serial |
7476 |
Permanent link to this record |
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|
|
Author |
Godoi, A.F.L.; Vilegas, W.; Godoi, R.H.M.; Van Vaeck, L.; Van Grieken, R. |
Title |
Application of low-pressure gas chromatography-io-trap mass spectrometry to the analysis of the eseential oil of Turnera diffusa (Ward.) Urb |
Type |
A1 Journal article |
Year |
2004 |
Publication |
Journal of chromatography: A: bibliography section |
Abbreviated Journal |
|
Volume |
1027 |
Issue |
|
Pages |
127-130 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
|
Address |
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Corporate Author |
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Thesis |
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Publisher |
|
Place of Publication |
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Editor |
|
Language |
|
Wos |
000188498900018 |
Publication Date |
2003-10-14 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
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Series Issue |
|
Edition |
|
ISSN |
|
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:43529 |
Serial |
7480 |
Permanent link to this record |
|
|
|
Author |
Potgieter-Vermaak, S.S.; Potgieter, J.H.; Van Grieken, R. |
Title |
The application of Raman spectrometry to investigate and characterize cement: part I: a review |
Type |
A1 Journal article |
Year |
2006 |
Publication |
Cement and concrete research |
Abbreviated Journal |
|
Volume |
36 |
Issue |
4 |
Pages |
656-662 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
|
Address |
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Corporate Author |
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Thesis |
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Publisher |
|
Place of Publication |
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Editor |
|
Language |
|
Wos |
000236781200006 |
Publication Date |
2005-11-03 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0008-8846 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:57470 |
Serial |
7482 |
Permanent link to this record |
|
|
|
Author |
Potgieter-Vermaak, S.S.; Potgieter, J.H.; Belleil, M.; DeWeerdt, F.; Van Grieken, R. |
Title |
The application of Raman spectrometry to the investigation of cement: part 2: a micro-Raman study of OPC, slag and fly ash |
Type |
A1 Journal article |
Year |
2006 |
Publication |
Cement and concrete research |
Abbreviated Journal |
|
Volume |
36 |
Issue |
4 |
Pages |
663-670 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
|
Address |
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Corporate Author |
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Thesis |
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Publisher |
|
Place of Publication |
|
Editor |
|
Language |
|
Wos |
000236781200007 |
Publication Date |
2005-11-03 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0008-8846 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:57471 |
Serial |
7483 |
Permanent link to this record |
|
|
|
Author |
Osán, J.; Kurunczi, S.; Török, S.; Worobiec, A.; Van Grieken, R. |
Title |
Application of thin-window EPMA to environmental problems in Hungary |
Type |
A1 Journal article |
Year |
2002 |
Publication |
Microchimica acta |
Abbreviated Journal |
|
Volume |
139 |
Issue |
|
Pages |
111-117 |
Keywords |
A1 Journal article; Laboratory Experimental Medicine and Pediatrics (LEMP); AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
|
Address |
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Corporate Author |
|
Thesis |
|
Publisher |
|
Place of Publication |
|
Editor |
|
Language |
|
Wos |
000175560300017 |
Publication Date |
2003-03-05 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0026-3672; 1436-5073 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:39521 |
Serial |
7484 |
Permanent link to this record |
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|
|
Author |
Jambers, W.; de Bock, L.; Van Grieken, R. |
Title |
Applications of micro-analysis to individual environmental particles |
Type |
A1 Journal article |
Year |
1996 |
Publication |
Fresenius' journal of analytical chemistry |
Abbreviated Journal |
|
Volume |
355 |
Issue |
|
Pages |
521-527 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
|
Address |
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Corporate Author |
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Thesis |
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Publisher |
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Place of Publication |
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Editor |
|
Language |
|
Wos |
A1996UV61000015 |
Publication Date |
2004-03-24 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0937-0633; 1432-1130 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:14653 |
Serial |
7486 |
Permanent link to this record |
|
|
|
Author |
Cardell, C.; Yebra, A.; Van Grieken, R.E. |
Title |
Applying digital image processing to SEM-EDX and BSE images to determine and quantify porosity and salts with depth in porous media |
Type |
A1 Journal article |
Year |
2002 |
Publication |
Microchimica acta |
Abbreviated Journal |
|
Volume |
140 |
Issue |
|
Pages |
9-14 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
|
Address |
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Corporate Author |
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Thesis |
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Publisher |
|
Place of Publication |
|
Editor |
|
Language |
|
Wos |
000178757500003 |
Publication Date |
2003-03-05 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
|
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:40619 |
Serial |
7487 |
Permanent link to this record |
|
|
|
Author |
Bencs, L.; Ravindra, K.; de Hoog, J.; Spolnik, Z.; Bleux, N.; Berghmans, P.; Deutsch, F.; Roekens, E.; Van Grieken, R. |
Title |
Appraisal of measurement methods, chemical composition and sources of fine atmospheric particles over six different areas of Northern Belgium |
Type |
A1 Journal article |
Year |
2010 |
Publication |
Environmental pollution |
Abbreviated Journal |
|
Volume |
158 |
Issue |
11 |
Pages |
3421-3430 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
Daily and seasonal variation in the total elemental, organic carbon (OC) and elemental carbon (EC) content and mass of PM2.5 were studied at industrial, urban, suburban and agricultural/rural areas. Continuous (optical Dustscan, standard tapered element oscillating micro-balance (TEOM), TEOM with filter dynamics measurement system), semi-continuous (Partisol filter-sampling) and non-continuous (Dekati-impactor sampling and gravimetry) methods of PM2.5 mass monitoring were critically evaluated. The average elemental fraction accounted for 26% of the PM2.5 mass measured by gravimetry. Metals, like K, Mn, Fe, Cu, Zn and Pb were strongly inter-correlated, also frequently with non-metallic elements (P, S, Cl and/or Br) and EC/OC. A high OC/EC ratio (29) was generally observed. The total carbon content of PM2.5 ranged between 3 and 77% (averages: 1232%), peaking near industrial/heavy trafficked sites. Principal component analysis identified heavy oil burning, ferrous/non-ferrous industry and vehicular emissions as the main sources of metal pollution. This work compares various aerosol monitoring methods to characterize PM2.5 over six locations of different anthropogenic activities over Northern Belgium. |
Address |
|
Corporate Author |
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Thesis |
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Publisher |
|
Place of Publication |
|
Editor |
|
Language |
|
Wos |
000282563200009 |
Publication Date |
2010-08-23 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0269-7491; 1873-6424 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:84237 |
Serial |
7488 |
Permanent link to this record |
|
|
|
Author |
Daems, E.; Dewaele, D.; Barylyuk, K.; De Wael, K.; Sobott, F. |
Title |
Aptamer-ligand recognition studied by native ion mobility-mass spectrometry |
Type |
A1 Journal article |
Year |
2021 |
Publication |
Talanta |
Abbreviated Journal |
Talanta |
Volume |
224 |
Issue |
|
Pages |
121917 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
The range of applications for aptamers, small oligonucleotide-based receptors binding to their targets with high specificity and affinity, has been steadily expanding. Our understanding of the mechanisms governing aptamer-ligand recognition and binding is however lagging, stymieing the progress in the rational design of new aptamers and optimization of the known ones. Here we demonstrate the capabilities and limitations of native ion mobility-mass spectrometry for the analysis of their higher-order structure and non-covalent interactions. A set of related cocaine-binding aptamers, displaying a range of folding properties and ligand binding affinities, was used as a case study in both positive and negative electrospray ionization modes. Using carefully controlled experimental conditions, we probed their conformational behavior and interactions with the high-affinity ligand quinine as a surrogate for cocaine. The ratios of bound and unbound aptamers in the mass spectra were used to rank them according to their apparent quinine-binding affinity, qualitatively matching the published ranking order. The arrival time differences between the free aptamer and aptamer-quinine complexes were consistent with a small ligand-induced conformational change, and found to inversely correlate with the affinity of binding. This mass spectrometry-based approach provides a fast and convenient way to study the molecular basis of aptamer-ligand recognition. |
Address |
|
Corporate Author |
|
Thesis |
|
Publisher |
|
Place of Publication |
|
Editor |
|
Language |
|
Wos |
000600787800122 |
Publication Date |
2020-12-02 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0039-9140; 1873-3573 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
4.162 |
Times cited |
|
Open Access |
OpenAccess |
Notes |
|
Approved |
Most recent IF: 4.162 |
Call Number |
UA @ admin @ c:irua:174086 |
Serial |
7490 |
Permanent link to this record |
|
|
|
Author |
Stefan, G.; Hosu, O.; De Wael, K.; Jesus Lobo-Castanon, M.; Cristea, C. |
Title |
Aptamers in biomedicine : selection strategies and recent advances |
Type |
A1 Journal article |
Year |
2021 |
Publication |
Electrochimica Acta |
Abbreviated Journal |
Electrochim Acta |
Volume |
376 |
Issue |
|
Pages |
137994 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
Aptamers have come in the spotlight as bio-mimetic molecular recognition elements in the field of biomedicine due to various applications in diagnostics, drug delivery, therapeutics, and pharmaceutical analysis. Aptamers are composed of nucleic acid strands (DNA or RNA) that can specifically interact in a three-dimensional tailored design with the target molecule. The basic method to generate aptamers is Systematic Evolution of Ligands by Exponential Enrichment (SELEX). Recent technological advances in aptamer selection allow for faster and cheaper production of a new generation of high-affinity aptamers compared to the traditional SELEX, which can last up to several months. Rigorous characterization performed by multiple research groups endorsed several well-defined aptamer sequences. Binding affinity, nature of the biomolecular interactions and structural characterization are of paramount importance for aptamer screening and development of applications. However, remarkable challenges still need to be dealt with before the aptamers can make great contributions to the biomedical field. Poor specificity and sensitivity, questionable clinical use, low drug loading, in vivo stability and toxicity are only some of the identified challenges. This review accounts for the 30th celebration of the SELEX technology underlining the most important aptamers' achievements in the biomedical field within mostly the past five years. Aptamers' advantages over antibodies are discussed. Because of potential clinical translational utility, insights of remarkable developments in aptamer-based methods for diagnosis and monitoring of disease biomarkers and pharmaceuticals are discussed focusing on the recent studies (2015-2020). The current challenges and promising opportunities for aptamers for therapeutic and theragnostic purposes are also presented. (C) 2021 Elsevier Ltd. All rights reserved. |
Address |
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Corporate Author |
|
Thesis |
|
Publisher |
|
Place of Publication |
|
Editor |
|
Language |
|
Wos |
000634761900003 |
Publication Date |
2021-02-22 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0013-4686 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
4.798 |
Times cited |
|
Open Access |
Not_Open_Access |
Notes |
|
Approved |
Most recent IF: 4.798 |
Call Number |
UA @ admin @ c:irua:177677 |
Serial |
7491 |
Permanent link to this record |
|
|
|
Author |
Darchuk, L.; Tsybrii, Z.; Worobiec, A.; Vázquez, C.; Palacios, O.M.; Stefaniak, E.A.; Gatto Rotondo, G.; Sizov, F.; Van Grieken, R. |
Title |
Argentinean prehistoric pigments' study by combined SEM/EDX and molecular spectroscopy |
Type |
A1 Journal article |
Year |
2010 |
Publication |
Spectrochimica acta: part A: molecular and biomolecular spectroscopy |
Abbreviated Journal |
|
Volume |
75 |
Issue |
5 |
Pages |
1398-1402 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Laboratory Experimental Medicine and Pediatrics (LEMP) |
Abstract |
Composition of the prehistoric pigments (from Carriqueo rock shelter, Rio Negro province, Argentina) has been analysed by means of molecular spectroscopy (Fourier transform infrared (FTIR) and micro-Raman) and scanning electron microscopy (SEM) coupled to an energy-dispersive X-ray spectrometer (EDS). Red and yellow pigments were recognized as red and yellow ochre. The matrix of the pigments is composed of one or more substances. According to the matrix composition yellow and red pigments were also divided into two groupsi.e. those containing kaolinite or sulphates. Green pigment was detected as green earth, made up of celadonite as a chromophore. |
Address |
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Corporate Author |
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Thesis |
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Publisher |
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Place of Publication |
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Editor |
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Language |
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Wos |
000277231700004 |
Publication Date |
2010-02-05 |
Series Editor |
|
Series Title |
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Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
1386-1425 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:81939 |
Serial |
7493 |
Permanent link to this record |
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|
|
Author |
Semenov, M.Y.; Khodzher, T.V.; Obolkin, V.A.; Domysheva, V.M.; Golobokova, L.P.; Kobeleva, N.A.; Netsvetaeva, O.G.; Potemkin, V.L.; Van Grieken, R.; Fukuzaki, N. |
Title |
Assessing the acidification risk in the Lake Baikal region |
Type |
A1 Journal article |
Year |
2006 |
Publication |
Chemistry and ecology |
Abbreviated Journal |
|
Volume |
22 |
Issue |
1 |
Pages |
1-11 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
|
Address |
|
Corporate Author |
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Thesis |
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Publisher |
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Place of Publication |
|
Editor |
|
Language |
|
Wos |
000236110800001 |
Publication Date |
2006-03-02 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0275-7540 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:56510 |
Serial |
7496 |
Permanent link to this record |
|
|
|
Author |
Blockhuys, F.; Claes, M.; Van Grieken, R.; Geise, H.J. |
Title |
Assessing the molecular weight of a conducting polymer by grazing emission XRF |
Type |
A1 Journal article |
Year |
2000 |
Publication |
Analytical chemistry |
Abbreviated Journal |
|
Volume |
72 |
Issue |
14 |
Pages |
3366-3368 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
|
Address |
|
Corporate Author |
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Thesis |
|
Publisher |
|
Place of Publication |
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Editor |
|
Language |
|
Wos |
000088347100054 |
Publication Date |
2002-07-26 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0003-2700; 5206-882x |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:27915 |
Serial |
7497 |
Permanent link to this record |
|
|
|
Author |
Semenov, M.Y.; Spolnik, Z.; Van Grieken, R. |
Title |
Assessing the size-dependent chemical speciation of soil particles using electron probe X-ray microanalysis |
Type |
A1 Journal article |
Year |
2007 |
Publication |
Microchimica acta |
Abbreviated Journal |
|
Volume |
157 |
Issue |
3/4 |
Pages |
121-126 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
|
Address |
|
Corporate Author |
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Thesis |
|
Publisher |
|
Place of Publication |
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Editor |
|
Language |
|
Wos |
000244691600001 |
Publication Date |
2006-07-26 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0026-3672; 1436-5073 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:63400 |
Serial |
7498 |
Permanent link to this record |
|
|
|
Author |
Godoi, R.H.M.; Potgieter-Vermaak, S.; Godoi, A.F.L.; Stranger, M.; Van Grieken, R. |
Title |
Assessment of aerosol particles within the Rubens' House Museum in Antwerp, Belgium |
Type |
A1 Journal article |
Year |
2008 |
Publication |
X-ray spectrometry |
Abbreviated Journal |
|
Volume |
37 |
Issue |
4 |
Pages |
298-303 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
The majority of researchers, conservators and curators recognise that atmospheric pollution is one of the major threats to works of art. In principle, all atmospheric particles, when deposited onto art objects can be considered harmful because of their potential in causing deterioration. Moreover, under certain conditions, particulate matter can induce and intensify surface damage, particularly because of its potential to serve as centre for moisture condensation and adsorbent of gaseous pollutants. To investigate the potential harm that these particles can cause, comprehensive characterisation of the particulate matter is necessary. Particulate matter was collected at the Rubens' House Museum in Antwerp, Belgium, where a unique exhibit of the paintings and living quarters of Peter Paul Rubens (1577-1640) are seen. Size segregated aerosol samples were collected for analyses of bulk and single particle elemental and molecular compositions. They were analysed by electron probe micro-analysis, utilising facilities for low-Z element determination, and by energy-dispersive x-ray fluorescence, to investigate the elemental composition of individual particles and bulk samples, and by micro Raman spectrometry, to elucidate the molecular composition. Results are interpreted separately and as a whole with the specific aim of identifying compounds that could contribute to the chemical reactions taking place on the surfaces of artefacts and which could potentially cause degradation of the objects. |
Address |
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Corporate Author |
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Thesis |
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Publisher |
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Place of Publication |
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Editor |
|
Language |
|
Wos |
000258670600004 |
Publication Date |
2008-03-10 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0049-8246 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:69494 |
Serial |
7499 |
Permanent link to this record |
|
|
|
Author |
Ravindra, K.; Wauters, E.; Tyagi, S.K.; Mor, S.; Van Grieken, R. |
Title |
Assessment of air quality after the implementation of Compressed Natural Gas (CNG) as fuel in public transport in Delhi, India |
Type |
A1 Journal article |
Year |
2006 |
Publication |
Environmental monitoring and assessment |
Abbreviated Journal |
|
Volume |
115 |
Issue |
|
Pages |
405-417 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
|
Address |
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Corporate Author |
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Thesis |
|
Publisher |
|
Place of Publication |
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Editor |
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Language |
|
Wos |
000238973500023 |
Publication Date |
2006-04-13 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
1420-2026; 1573-2967 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:58856 |
Serial |
7501 |
Permanent link to this record |
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|
|
Author |
Idris, A.M.; Eltayeb, M.A.H.; Potgieter-Vermaak, S.S.; Van Grieken, R.; Potgieter, J.H. |
Title |
Assessment of heavy metals pollution in Sudanese harbours along the Red Sea Coast |
Type |
A1 Journal article |
Year |
2007 |
Publication |
Microchemical journal |
Abbreviated Journal |
|
Volume |
87 |
Issue |
2 |
Pages |
104-112 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
|
Address |
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Corporate Author |
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Thesis |
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Publisher |
|
Place of Publication |
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Editor |
|
Language |
|
Wos |
000251750000003 |
Publication Date |
2007-07-05 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
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Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0026-265x; 0026-265x |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:66067 |
Serial |
7504 |
Permanent link to this record |
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|
|
Author |
Ro, C.-U.; Hoornaert, S.; Van Grieken, R. |
Title |
Assessment of homogeneity of candidate reference material at the nanogram level and investigation on representativeness of single particle analysis using electron probe X-ray microanalysis |
Type |
A1 Journal article |
Year |
1999 |
Publication |
Analytica chimica acta |
Abbreviated Journal |
|
Volume |
389 |
Issue |
|
Pages |
151-160 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
|
Address |
|
Corporate Author |
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Thesis |
|
Publisher |
|
Place of Publication |
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Editor |
|
Language |
|
Wos |
000080527900016 |
Publication Date |
2002-07-25 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0003-2670; 1873-4324 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:27587 |
Serial |
7506 |
Permanent link to this record |
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|
|
Author |
van Roy, W.; Struyf, H.; Kennis, P.; Van Vaeck, L.; Van Grieken, R.; Andrle, C. |
Title |
Assessment of local analysis by Fourier transform laser microprobe mass spectrometry with external ion source |
Type |
A1 Journal article |
Year |
1995 |
Publication |
Microchimica acta |
Abbreviated Journal |
|
Volume |
120 |
Issue |
|
Pages |
121-137 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
|
Address |
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Corporate Author |
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Thesis |
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Publisher |
|
Place of Publication |
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Editor |
|
Language |
|
Wos |
A1995TH37000012 |
Publication Date |
2005-02-26 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0026-3672; 1436-5073 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:12356 |
Serial |
7507 |
Permanent link to this record |
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|
|
Author |
Janssen, N.A.H.; Lanki, T.; Hoek, G.; Vallius, M.; de Hartog, J.J.; Van Grieken, R.; Pekkanen, J.; Brunekreef, B. |
Title |
Associations between ambient, personal, and indoor exposure to fine particulate matter constituents in Dutch and Finnish panels of cardiovascular patients |
Type |
A1 Journal article |
Year |
2005 |
Publication |
Occupational and environmental medicine |
Abbreviated Journal |
|
Volume |
62 |
Issue |
|
Pages |
868-877 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
|
Address |
|
Corporate Author |
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Thesis |
|
Publisher |
|
Place of Publication |
|
Editor |
|
Language |
|
Wos |
000233368000010 |
Publication Date |
2005-11-18 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
1351-0711 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:55125 |
Serial |
7509 |
Permanent link to this record |
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|
|
Author |
de Hartog, J.J.; Lanki, T.; Timonen, K.L.; Hoek, G.; Janssen, N.A.H.; Ibald-Mulli, A.; Peters, A.; Heinrich, J.; Tarkainen, T.H.; Van Grieken, R.; van Wijnen, J.H.; Brunekreef, B.; Pekkanen, J. |
Title |
Associations between PM2.5 and heart rate variability are modified by particle composition and beta-blocker use in patients with coronary heart disease |
Type |
A1 Journal article |
Year |
2009 |
Publication |
Environmental health perspectives |
Abbreviated Journal |
|
Volume |
117 |
Issue |
1 |
Pages |
105-111 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
Background: It has been hypothesized that ambient particulate air pollution is able to modify the autonomic nervous control of the heart, measured as heart rate variability (HRV) . Previously we reported heterogeneous associations between particulate matter with aerodynamic diameter < 2.5 µm (PM2.5) and HRV across three study centers. Objective: We evaluated whether exposure misclassification, effect modification by medication, or differences in particle composition could explain the inconsistencies. Methods: Subjects with coronary heart disease visited clinics biweekly in Amsterdam, the Netherlands ; Erfurt, Germany ; and Helsinki, Finland for 68 months. The standard deviation (SD) of NN intervals on an electrocardiogram (ECG ; SDNN) and high frequency (HF) power of HRV was measured with ambulatory ECG during paced breathing. Outdoor levels of PM2.5 were measured at a central site. In Amsterdam and Helsinki, indoor and personal PM2.5 were measured during the 24 hr preceding the clinic visit. PM2.5 was apportioned between sources using principal component analyses. We analyzed associations of indoor/personal PM2.5, elements of PM2.5, and source-specific PM2.5 with HRV using linear regression. Results: Indoor and personal PM2.5 were not associated with HRV. Increased outdoor PM2.5 was associated with decreased SDNN and HF at lags of 2 and 3 days only among persons not using beta-blocker medication. Traffic-related PM2.5 was associated with decreased SDNN, and long-range transported PM2.5 with decreased SDNN and HF, most strongly among persons not using beta blockers. Indicators for PM2.5 from traffic and long-range transport were also associated with decreased HRV. Conclusions: Our results suggest that differences in the composition of particles, beta-blocker use, and obesity of study subjects may explain some inconsistencies among previous studies on HRV. |
Address |
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Corporate Author |
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Thesis |
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Publisher |
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Place of Publication |
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Editor |
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Language |
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Wos |
000262483900037 |
Publication Date |
2008-08-25 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0091-6765; 1552-9924 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:72924 |
Serial |
7510 |
Permanent link to this record |
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|
|
Author |
Buczyńska, A.J.; Krata, A.; Stranger, M.; Godoi, A.F.L.; Kontozova-Deutsch, V.; Bencs, L.; Naveau, I.; Roekens, E.; Van Grieken, R. |
Title |
Atmospheric BTEX-concentrations in an area with intensive street traffic |
Type |
A1 Journal article |
Year |
2009 |
Publication |
Atmospheric environment : an international journal |
Abbreviated Journal |
|
Volume |
43 |
Issue |
2 |
Pages |
311-318 |
Keywords |
A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
Abstract |
The major threat to clean air in developed and industrializing countries is now posed by traffic emissions. The effects of traffic road modifications on the air quality are, however, rarely reported in the literature. The aim of this study was to determine the influence of the modernization and renovation of a traffic artery in the region of Mortsel (Antwerp, Belgium) on the concentration of volatile organic compounds such as: benzene, toluene, ethylbenzene and m-, p-, o-xylenes (BTEX). The original goal of the reconstruction works was to reduce the traffic lanes of one of the busiest streets in Antwerp, in order to discourage the road traffic and in consequence also to improve the air quality in this region. The average concentrations of BTEX before these works in 2003 were: 1.6, 7.0, 0.9, 2.3, and 0.9 ìg/m3, for benzene, toluene, ethylbenzene, m + p xylenes, and o-xylene, respectively. However, after the completion of the works, in 2005, they were slightly higher: 2.5, 9.5, 1.6, 3.4, and 1.3 ìg/m3, respectively. The scatter plots of benzene against toluene, ethylbenzene and xylenes in 2003 and 2005 showed very good correlations. This fact indicated that all of the measured compounds originated from the same source, namely the road traffic. Moreover, the data obtained from an air-monitoring station at less than 6 km distance from the sampling site (operated by the Flemish Environment Agency, and located in Borgerhout, Antwerp), confirmed the lack of influence of background concentrations of BTEX. The obtained results led to the conclusion that the reduction of the number of traffic lanes had apparently increased the traffic jams and also increased the emission from cars. Therefore, these modernization works had even a negative impact on the local concentration of traffic-related pollutants as BTEX. |
Address |
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Corporate Author |
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Thesis |
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Publisher |
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Place of Publication |
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Editor |
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Language |
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Wos |
000262956500011 |
Publication Date |
2008-10-18 |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
1352-2310 |
ISBN |
|
Additional Links |
UA library record; WoS full record; WoS citing articles |
Impact Factor |
|
Times cited |
|
Open Access |
|
Notes |
|
Approved |
no |
Call Number |
UA @ admin @ c:irua:72925 |
Serial |
7518 |
Permanent link to this record |