| Records |
Author  |
Van Grieken, R.; Janssens, K.; Van 't dack, L.; Meersman, G. |
| Title |
Art 2002 : 7th International Conference on Non-destructive Testing and Microanalysisfor the Diagnostics and Conservation of the Cultural and Environmental Heritage, 2-6 June 2002, Congress Centre Elzenveld, Antwerp, Belgium |
Type |
ME3 Book as editor |
| Year |
2002 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
780 p. |
| Keywords |
ME3 Book as editor; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Approved |
Most recent IF: NA |
| Call Number |
UA @ admin @ c:irua:39523 |
Serial |
5478 |
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| Author |
Van Grieken, R.; Janssens, K.; van Espen, P.; Injuk, J.; Padilla, R.; Vittiglio, G.; Potgieter, J.H. |
| Title |
Novel quantitative procedures for in-situ X-ray fluorescence analysis |
Type |
H3 Book chapter |
| Year |
2005 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
45-60 |
| Keywords |
H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Chemometrics (Mitac 3) |
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Open Access |
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| Notes |
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Approved |
Most recent IF: NA |
| Call Number |
UA @ admin @ c:irua:54563 |
Serial |
5751 |
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| Author |
Van Grieken, R.; Kontozova, V.; Godoi, R.H.M.; Spolnik, Z.; Worobiec, A.; Deutsch, F.; Bencs, L. |
| Title |
Some studies of the effect of indoor and outdoor pollutants on cultural heritage items |
Type |
P3 Proceeding |
| Year |
2005 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
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| Keywords |
P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Laboratory Experimental Medicine and Pediatrics (LEMP) |
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Approved |
no |
| Call Number |
UA @ admin @ c:irua:57632 |
Serial |
8556 |
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| Author |
Van Grieken, R.; Makarovska, Y.; van Meel, K.; Worobiec, A. |
| Title |
X-ray spectrometry for analysis of atmospheric particulate matter: detection limits versus legal levels |
Type |
H3 Book chapter |
| Year |
2007 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
153-161
T2 - Topics in X-ray spectrometry / Vázque |
| Keywords |
H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Laboratory Experimental Medicine and Pediatrics (LEMP) |
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| Notes |
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Approved |
no |
| Call Number |
UA @ admin @ c:irua:64402 |
Serial |
8784 |
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| Author |
Van Grieken, R.; Robberecht, H.; Shani, J.; Van Dyck, P.; Vos, L. |
| Title |
Energy-dispersive X-ray fluorescence for direct trace analysis of biomedical and environmental samples |
Type |
H3 Book chapter |
| Year |
1982 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
159-178
T2 - X-ray fluorescence (XRF and PIXE) in |
| Keywords |
H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Open Access |
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| Notes |
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Approved |
no |
| Call Number |
UA @ admin @ c:irua:117485 |
Serial |
7904 |
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| Author |
Van Grieken, R.; Shevah, Y. |
| Title |
Atmospheric deposition and its impact on ecosystems, with particular reference to the Mid-East: proceedings of a symposium held in Tel-Aviv, Israel, on 5-6 June 2000, under the auspices of IUPAC |
Type |
ME3 Book as editor |
| Year |
2002 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
170 p. |
| Keywords |
ME3 Book as editor; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Edition |
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ISBN |
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Times cited |
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Open Access |
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| Notes |
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Approved |
no |
| Call Number |
UA @ admin @ c:irua:40621 |
Serial |
7521 |
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| Author |
Van Grieken, R.; Torfs, K. |
| Title |
Atmospheric aerosols and deposition near historic buildings: chemistry, sources, interrelationships and relevance |
Type |
P3 Proceeding |
| Year |
1996 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
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| Keywords |
P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Editor |
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Wos |
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Series Issue |
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Edition |
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ISBN |
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Additional Links |
UA library record |
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Times cited |
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Open Access |
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| Notes |
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Approved |
no |
| Call Number |
UA @ admin @ c:irua:14662 |
Serial |
7515 |
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| Author |
Van Grieken, R.; Verbueken, A.; Bruynseels, F.; Vandeputte, D.; Goossenaerts, C.; Leysen, L.; Otten, P.; Wouters, L. |
| Title |
Laser microprobe mass analysis : characteristics and applications |
Type |
P3 Proceeding |
| Year |
1987 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
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| Keywords |
P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
| Abstract |
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Place of Publication |
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Editor |
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Wos |
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Series Title |
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Series Issue |
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Edition |
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ISBN |
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Additional Links |
UA library record |
| Impact Factor |
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Times cited |
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Open Access |
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| Notes |
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Approved |
no |
| Call Number |
UA @ admin @ c:irua:117534 |
Serial |
8155 |
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| Author |
Van Grieken, R.; Vleugels, G.; Roekens, E.; Veny, P. |
| Title |
Modern micro-analytical techniques to elucidate the causes and mechanisms of damage to cultural property |
Type |
H3 Book chapter |
| Year |
1991 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
101-110
T2 - Science, technology and European cult |
| Keywords |
H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
| Abstract |
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Thesis |
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| Publisher |
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Place of Publication |
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Editor |
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Wos |
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Publication Date |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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ISBN |
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Additional Links |
UA library record |
| Impact Factor |
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Times cited |
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Open Access |
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| Notes |
|
Approved |
no |
| Call Number |
UA @ admin @ c:irua:681 |
Serial |
8270 |
| Permanent link to this record |
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| Author |
Van Grieken, R.; Wollast, R. |
| Title |
Progress in Belgian oceanographic research : proceedings of symposium, Brussels, 3-5 March 1985 |
Type |
ME3 Book as editor |
| Year |
1985 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
479 p. |
| Keywords |
ME3 Book as editor; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
| Abstract |
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| Address |
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Thesis |
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| Publisher |
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Place of Publication |
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Editor |
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Wos |
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Publication Date |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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ISBN |
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Additional Links |
UA library record |
| Impact Factor |
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Times cited |
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Open Access |
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| Notes |
|
Approved |
no |
| Call Number |
UA @ admin @ c:irua:117474 |
Serial |
8422 |
| Permanent link to this record |
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| |
| Author |
Van Grieken, R.E. |
| Title |
X-ray spectrometry |
Type |
H3 Book chapter |
| Year |
2000 |
Publication |
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Abbreviated Journal |
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| Volume |
15 |
Issue |
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Pages |
13269-13443
T2 - Encyclopedia of analytical chemis |
| Keywords |
H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
| Abstract |
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| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
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Editor |
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Wos |
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Publication Date |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
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ISBN |
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Additional Links |
UA library record |
| Impact Factor |
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Times cited |
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Open Access |
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| Notes |
|
Approved |
no |
| Call Number |
UA @ admin @ c:irua:31650 |
Serial |
8775 |
| Permanent link to this record |
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| Author |
Van Grieken, R.E.; LaBrecque, J.J. |
| Title |
Trace analysis of environmental samples by X-ray emission spectroscopy |
Type |
H3 Book chapter |
| Year |
1985 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
101-183
T2 - Trace analysis : vol. 4 / Lawrence, J |
| Keywords |
H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
| Abstract |
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| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
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Editor |
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Wos |
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Publication Date |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
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ISBN |
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Additional Links |
UA library record |
| Impact Factor |
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Times cited |
|
Open Access |
|
| Notes |
|
Approved |
no |
| Call Number |
UA @ admin @ c:irua:117495 |
Serial |
8686 |
| Permanent link to this record |
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| Author |
Van Grieken, R.E.; Markowicz, A.A. |
| Title |
Handbook of X-ray spectrometry |
Type |
ME2 Book as editor or co-editor |
| Year |
2002 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
1016 p. |
| Keywords |
ME2 Book as editor or co-editor; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
| Abstract |
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| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
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Editor |
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| Language |
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Wos |
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Publication Date |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
2 ed. |
| ISSN |
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ISBN |
0-8247-0600-5 |
Additional Links |
UA library record |
| Impact Factor |
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Times cited |
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Open Access |
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| Notes |
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Approved |
no |
| Call Number |
UA @ admin @ c:irua:36390 |
Serial |
8017 |
| Permanent link to this record |
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| Author |
Van Hal, M. |
| Title |
Photo(electro)catalytic air purification and soot degradation with simultaneous energy recovery |
Type |
Doctoral thesis |
| Year |
2021 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
XXXII, 203 p. |
| Keywords |
Doctoral thesis; Engineering sciences. Technology; Sustainable Energy, Air and Water Technology (DuEL) |
| Abstract |
Today’s society is increasingly challenged by a range of urgent environmental problems. Air pollution is one of these pressing topics. This thesis will mainly focus on the degradation of volatile organic compounds (VOCs) and particulate matter (PM) – more specifically soot. A second globally urging topic is the quest for sustainable energy production. To simultaneously target both environmental problems, a photoelectrochemical (PEC) cell will be studied in this thesis, combining air purification and sustainable energy production in a single device. Photocatalysis is used at the anode of the PEC cell to drive the air purification process, while the energy contained in the degraded compounds is (partially) recovered at the cathode, either as H2 gas or electricity. The first two experimental chapters focus on the proof of concept of such an unbiased all-gas phase PEC cell targeting VOC degradation, using both TiO2- and WO3-based photocatalysts. In the two following experimental chapters the photocatalytic soot oxidation capacity of these TiO2- and WO3-based photocatalysts was studied. In the final experimental chapter the previously obtained results were combined, striving towards an efficient, sunlight-driven and soot-degrading waste gas-to-energy PEC cell. |
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Wos |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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ISBN |
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Additional Links |
UA library record |
| Impact Factor |
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Times cited |
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Open Access |
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| Notes |
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Approved |
Most recent IF: NA |
| Call Number |
UA @ admin @ c:irua:184521 |
Serial |
8378 |
| Permanent link to this record |
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| Author |
Van Havenbergh, K. |
| Title |
Influence of silicon nanoparticle coating on the electrolyte decomposition in Li-ion batteries |
Type |
Doctoral thesis |
| Year |
2015 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
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| Keywords |
Doctoral thesis; Electron microscopy for materials research (EMAT) |
| Abstract |
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| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
Antwerpen |
Editor |
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| Language |
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Wos |
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Publication Date |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
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ISBN |
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Additional Links |
UA library record |
| Impact Factor |
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Times cited |
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Open Access |
|
| Notes |
|
Approved |
Most recent IF: NA |
| Call Number |
UA @ lucian @ c:irua:131647 |
Serial |
4196 |
| Permanent link to this record |
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| |
| Author |
Van Hoecke, L. |
| Title |
CFD-Assisted design of fluidized reactors for H2 release from LOHC |
Type |
Doctoral thesis |
| Year |
2024 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
|
Pages |
XXXIII, 181 p. |
| Keywords |
Doctoral thesis; Engineering sciences. Technology |
| Abstract |
Hydrogen (H2) is expected to become a key molecule in the transition towards a society running on renewable energy. It can be used to store excess renewable energy at peak production moments and release this energy at a later stage when renewable energy production is less. However, storing H2 is challenging due to the low density of this gas. As a solution, Liquid Organic Hydrogen Carriers or LOHC molecules have been proposed in the passed to increase volumetric energy density of H2. LOHC are a class of molecules that have storage sites available, to which the H2 gas can be chemically bounded. The LOHC molecule under investigation was dibenzyltoluene (DBT), which is an oil like liquid, that is easy to transport and poses little fire or explosion risks. To release the H2 from the DBT carrier, via a so-called dehydrogenation reaction, efficient mass and heat transfer is required during the process, since a large volume increase is expected from H2 release and the reaction is endothermic, i.e., a self – cooling process that takes place at temperatures around 300 C. The heat has to be supplied specifically to the active sites of catalyst particles that are present inside the reactor and which enable the dehydrogenation to proceed. For heat transfer limited processes fluidized bed reactors are often used, which is a type of reactor where the particle phase is being agitated by the fluid flow. The research proposed in this work, was to explore via computational fluid dynamics (CFD) simulations the possibilities and challenges of using fluidized bed reactors for the dehydrogenation of LOHC. The model selection required for CFD simulations of a three-phase system was investigated in this work, with a main emphasis on the drag model selection. The CFD modelling study was focused on the use of swirling fluidized bed reactors, since it was hypothesised that the swirling effect could also aid in increased removal of the gas phase from the reaction medium to increase the efficiency of the process. Ultimately, it was shown that the main challenges in the design of fluidized bed reactors will be to create uniform particle distribution inside the reactor. A new design for a dehydrogenation reactor is proposed based on the insights gained in this thesis. |
| Address |
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| Corporate Author |
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Thesis |
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Place of Publication |
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Editor |
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Wos |
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Publication Date |
2024-06-14 |
| Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
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ISBN |
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Additional Links |
UA library record |
| Impact Factor |
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Times cited |
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Open Access |
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| Notes |
|
Approved |
Most recent IF: NA |
| Call Number |
UA @ admin @ c:irua:205645 |
Serial |
9192 |
| Permanent link to this record |
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| Author |
Van Laer, K. |
| Title |
Numerical and experimental study of a packed bed plasma reactor for environmental applications |
Type |
Doctoral thesis |
| Year |
2017 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
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| Keywords |
Doctoral thesis; Plasma Lab for Applications in Sustainability and Medicine – Antwerp (PLASMANT) |
| Abstract |
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| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
Antwerpen |
Editor |
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| Language |
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Wos |
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Publication Date |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
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ISBN |
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Additional Links |
UA library record |
| Impact Factor |
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Times cited |
|
Open Access |
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| Notes |
|
Approved |
Most recent IF: NA |
| Call Number |
UA @ lucian @ c:irua:144061 |
Serial |
4675 |
| Permanent link to this record |
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| |
| Author |
van Landuyt, J. |
| Title |
High resolution electron microscopy for materials |
Type |
H3 Book chapter |
| Year |
1992 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
23-32 |
| Keywords |
H3 Book chapter; Electron microscopy for materials research (EMAT) |
| Abstract |
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| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
Eurem 92 |
Place of Publication |
Granada |
Editor |
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| Language |
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Wos |
000166175900005 |
Publication Date |
0000-00-00 |
| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
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ISBN |
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Additional Links |
UA library record; WoS full record; WoS citing articles |
| Impact Factor |
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Times cited |
7 |
Open Access |
|
| Notes |
|
Approved |
no |
| Call Number |
UA @ lucian @ c:irua:4097 |
Serial |
1448 |
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| Author |
van Landuyt, J.; Kuypers, S.; van Heurck, C.; Van Tendeloo, G.; Amelinckx, S. |
| Title |
Methods of structural analysis of modulated structures and quasicrystals |
Type |
H3 Book chapter |
| Year |
1993 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
|
Pages |
205-224 |
| Keywords |
H3 Book chapter; Electron microscopy for materials research (EMAT) |
| Abstract |
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| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
s.l. |
Editor |
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| Language |
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Wos |
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Publication Date |
0000-00-00 |
| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
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ISBN |
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Additional Links |
UA library record |
| Impact Factor |
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Times cited |
|
Open Access |
|
| Notes |
|
Approved |
no |
| Call Number |
UA @ lucian @ c:irua:6781 |
Serial |
2018 |
| Permanent link to this record |
| |
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| |
| Author |
van Landuyt, J.; van Bockstael, M.H.G.; van Royen, J. |
| Title |
Microscopy of gemmological materials |
Type |
H3 Book chapter |
| Year |
1997 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
293-320 |
| Keywords |
H3 Book chapter; Electron microscopy for materials research (EMAT) |
| Abstract |
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| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
Vch |
Place of Publication |
Weinheim |
Editor |
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| Language |
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Wos |
A1995BC72X00044 |
Publication Date |
0000-00-00 |
| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
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ISBN |
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Additional Links |
UA library record; WoS full record; WoS citing articles |
| Impact Factor |
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Times cited |
4 |
Open Access |
|
| Notes |
|
Approved |
Most recent IF: NA |
| Call Number |
UA @ lucian @ c:irua:21419 |
Serial |
2037 |
| Permanent link to this record |
| |
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| |
| Author |
van Landuyt, J.; Van Tendeloo, G. |
| Title |
Charcaterization by high-resolution transmission electron microscopy |
Type |
H3 Book chapter |
| Year |
1998 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
187-190 |
| Keywords |
H3 Book chapter; Electron microscopy for materials research (EMAT) |
| Abstract |
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| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
Stt |
Place of Publication |
Den Haag |
Editor |
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| Language |
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Wos |
A1990DC39700012 |
Publication Date |
0000-00-00 |
| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
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ISBN |
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Additional Links |
UA library record; WoS full record; |
| Impact Factor |
|
Times cited |
|
Open Access |
|
| Notes |
|
Approved |
Most recent IF: NA |
| Call Number |
UA @ lucian @ c:irua:29685 |
Serial |
335 |
| Permanent link to this record |
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| |
| Author |
van Landuyt, J.; Van Tendeloo, G. |
| Title |
HREM for characterisation of nanoscale microstructures |
Type |
P3 Proceeding |
| Year |
1998 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
|
Pages |
15-18 |
| Keywords |
P3 Proceeding; Electron microscopy for materials research (EMAT) |
| Abstract |
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| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
Kyoto |
Editor |
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| Language |
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Wos |
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Publication Date |
0000-00-00 |
| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
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ISBN |
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Additional Links |
UA library record |
| Impact Factor |
|
Times cited |
|
Open Access |
|
| Notes |
|
Approved |
Most recent IF: NA |
| Call Number |
UA @ lucian @ c:irua:25687 |
Serial |
1499 |
| Permanent link to this record |
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| |
| Author |
van Landuyt, J.; Vanhellemont, J. |
| Title |
High-resolution electron microscopy for semiconducting materials science |
Type |
H3 Book chapter |
| Year |
1994 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
1109-1147 |
| Keywords |
H3 Book chapter; Electron microscopy for materials research (EMAT) |
| Abstract |
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| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
Elsevier |
Place of Publication |
Amsterdam |
Editor |
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| Language |
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Wos |
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Publication Date |
0000-00-00 |
| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
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ISBN |
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Additional Links |
UA library record |
| Impact Factor |
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Times cited |
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Open Access |
|
| Notes |
|
Approved |
no |
| Call Number |
UA @ lucian @ c:irua:10008 |
Serial |
1449 |
| Permanent link to this record |
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| |
| Author |
Van Loenhout, J. |
| Title |
Targeting pancreatic ductal adenocarcinoma and glioblastoma with oxidative stress-mediated treatment strategies : focus on tumor cell death and modulation of the tumor microenvironment |
Type |
Doctoral thesis |
| Year |
2021 |
Publication |
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Abbreviated Journal |
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| Volume |
|
Issue |
|
Pages |
167 p. |
| Keywords |
Doctoral thesis; Plasma Lab for Applications in Sustainability and Medicine – Antwerp (PLASMANT); Center for Oncological Research (CORE) |
| Abstract |
Pancreatic ductal adenocarcinoma (PDAC) and glioblastoma multiforme (GBM) are two of the most malignant solid tumor types with poor survival rates, which underscore the urgency of novel and efficacious treatment strategies. Within the last decade, immunotherapy has been established as a breakthrough in cancer therapy. This mainly has been driven by the clinical data and approval associated with several immune checkpoint inhibitors (e.g. anti-CTLA-4 and anti-PD-1/L1). Despite the clinical benefit in specific tumor types, these inhibitors have not yet fulfilled their promise in low immunogenic tumors such as PDAC and GBM. Oxidative stress in cancer cells due to elevated reactive oxygen species (ROS) and an inability to balance intracellular redox state has recently been highlighted as promising target for anticancer treatment strategies with possible immunogenic effects. In this PhD dissertation, I investigated novel oxidative stress-mediated treatment approaches to target PDAC and GBM and to enhance immunogenicity by inducing immunogenic cell death (ICD). In the first part of this thesis (chapter 2), I reviewed the mechanistic responses of cancer cells towards different oxidative stress-inducing treatment strategies and their immunomodulating effects. The resulting literature demonstrated that different exogenous and endogenous ROS-inducing therapies show direct and indirect immunomodulating effects, which can be either immunostimulatory or immunosuppressive. One of the indirect immunostimulatory effects of the ROS-mediating therapies is the capacity of inducing immunogenic cell death (ICD) in tumor cells, which can increase the immunogenicity and consequently can trigger an antitumoral immune response. In chapter 3, I investigated a novel exogenous ROS-inducing treatment method, namely cold atmospheric plasma, to determine the therapeutic and ICD-inducing effects in PDAC, in vitro. I revealed that plasma-treated PBS (pPBS) has the potential to induce ICD in pancreatic cancer cells (PCCs) and to reduce the immunosuppressive tumor microenvironment (TME) by attacking the tumor supportive pancreatic stellate cells (PSCs). Although the cell death induced in PSCs was non-immunogenic as seen by the lack of danger-associated molecular patterns (DAMPs) emission and DC activation, I showed that pPBS could disrupt the physical barrier and lower the immunosuppressive secretion profile (lower TGF-β) of PSCs. In contrast, DAMPs were released by PCCs after treatment with pPBS which resulted in activation and maturation of DCs and a more immunostimulatory secretion profile (higher TNF-α, IFN-γ). Hence, indirect plasma treatment via pPBS has the potential to enhance immunogenicity in PDAC by triggering ICD and by attacking the immunosuppressive PSCs. Tumor cells can evolve adaptation mechanisms to protect themselves against intrinsic oxidative stress by upregulation of pro-survival molecules and their antioxidant defense system to maintain the redox balance. As such, tumor cells can become resistant towards exogenous ROS-inducing therapies, like plasma. Dual targeting of the redox balance of tumor cells by increasing exogenous levels of ROS and inhibiting the antioxidant defense system can maximally exploit ROS-mediated cell death mechanisms as therapeutic anticancer strategy. In this regard, cold atmospheric plasma was combined with auranofin, a thioredoxin reductase inhibitor, in GBM (chapter 4). A synergistic effect was shown after this combination treatment in 2D and 3D, however, in 3D only high concentrations of auranofin synergized with plasma treatment. I confirmed a ROS-mediated response after combination treatment, which was able to induce distinct cell death mechanisms, specifically apoptosis and ferroptosis. Additionally, the auranofin and plasma combined treatment strategy induced cell death, which resulted in an increased release of DAMPs. Together with the observed DC maturation, these results indicates the potential increase in immunogenicity, though, the phagocytotic capacity of DCs was inhibited by auranofin. In chapter 5, I evaluated this promising oxidative stress combination therapy in GBM, in vivo. A decrease in tumor kinetics and an increased survival in GBM-bearing mice was observed when auranofin was sequentially combined with direct plasma treatment. No T cell infiltration was observed after auranofin monotherapy. However, further characterization of the TME after the combination therapy is necessary to provide more insight in the immunogenic effects in vivo. In conclusion, this PhD dissertation comprises novel and important therapeutic and immunogenic insights in cold atmospheric plasma and auranofin as promising oxidative stress-mediated treatment strategies for low immunogenic tumors, like PDAC and GBM. These preclinical results provide a solid basis for future research towards combinations with immunotherapeutic approaches. |
| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
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Editor |
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| Language |
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Wos |
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Publication Date |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
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ISBN |
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Additional Links |
UA library record |
| Impact Factor |
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Times cited |
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Open Access |
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| Notes |
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Approved |
Most recent IF: NA |
| Call Number |
UA @ admin @ c:irua:181309 |
Serial |
8643 |
| Permanent link to this record |
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| |
| Author |
Van Loon, J.; De Jong, M.; De Wael, K.; Du Bois, E. |
| Title |
Transposing testing from lab to on-site environment : a case of cocaine powder sampling |
Type |
P3 Proceeding |
| Year |
2020 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
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| Keywords |
P3 Proceeding; Engineering sciences. Technology; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Product development |
| Abstract |
This paper reports on the transition process to convert a specific lab technique to the on-site, real-life environment. Bringing a lab test to an on-site environment involves many difficulties regarding to the context, people skills and environmental support. Within this project, a case about sampling for an electrochemical measurement, was investigated as a basis to reason upon some general conclusions related to the process of transposing lab-tests to an on-site environment. The current lab test was analysed and compared with a focus group discussion with future users. Based on the findings, assumptions for the new sampling technique in the specific case were formulated. New low-tech methods to achieve the sampling were extensively tested and verified. Starting from this chosen case an argumentation was set up to generalise the conclusions, by reasoning on other cases of products that already passed this transition to the field. Based on a comparison, we could discuss that the selected parameters related to impact of the context environment, of the people that should handle the tests, related to the reasons for transposing the technology, and related to the technology that will be transposed to the on-site environment, were of importance of almost all cases and can therefore be considered as context-independent and related to the transfer to on-site testing. |
| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
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Editor |
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| Language |
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Wos |
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Publication Date |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
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ISBN |
978-94-6384-131-3 |
Additional Links |
UA library record |
| Impact Factor |
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Times cited |
|
Open Access |
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| Notes |
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Approved |
Most recent IF: NA |
| Call Number |
UA @ admin @ c:irua:169896 |
Serial |
6637 |
| Permanent link to this record |
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| Author |
van Malderen, H.; de Bock, L.; Hoornaert, S.; Injuk, J.; Van Grieken, R. |
| Title |
Chemical characterisation, source identification and quantification of the input of atmospheric particulate matter into the North Sea |
Type |
H3 Book chapter |
| Year |
1996 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
103-112
T2 - Dialogue between scientists and users |
| Keywords |
H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
| Abstract |
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| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
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Editor |
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| Language |
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Wos |
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Publication Date |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
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ISBN |
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Additional Links |
UA library record |
| Impact Factor |
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Times cited |
|
Open Access |
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| Notes |
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Approved |
no |
| Call Number |
UA @ admin @ c:irua:14671 |
Serial |
7642 |
| Permanent link to this record |
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| Author |
van Malderen, H.; de Bock, L.; Injuk, J.; Xhoffer, C.; Van Grieken, R. |
| Title |
North Sea aerosol characterization by single particle analysis techniques |
Type |
H3 Book chapter |
| Year |
1993 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
119-135
T2 - Progress in Belgian oceanographic res |
| Keywords |
H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
| Abstract |
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| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
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Editor |
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| Language |
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Wos |
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Publication Date |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
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ISBN |
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Additional Links |
UA library record |
| Impact Factor |
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Times cited |
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Open Access |
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| Notes |
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Approved |
no |
| Call Number |
UA @ admin @ c:irua:6269 |
Serial |
8317 |
| Permanent link to this record |
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| Author |
Van Oijstaeijen, W. |
| Title |
Green infrastructure and local implementation : (green) bridging the gap between research and practice |
Type |
Administrative Services |
| Year |
2023 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
xvii, 194 p. |
| Keywords |
Administrative Services; Doctoral thesis; Engineering sciences. Technology; Engineering Management (ENM) |
| Abstract |
Climate change is an ever-increasing threat to our planet, with the urbanisation of previously open spaces exacerbating the issue. The loss of open space leads to a decrease in ecosystem services, which negatively impacts the liveability in urbanised environments, and beyond. The incorporation of green infrastructure (GI) into the built environment is acknowledged as an effective and multi-functional measure to make our living environment resilient and future-proof. Notwithstanding that the local level is essential for effective GI implementation, research into local decision making is very limited. This thesis therefore aims to address two significant gaps in the implementation of GI. The first objective is to bridge the science-policy gap by integrating scientific knowledge on ES and GI into local decision-making processes. In this context, the policy dimension within this thesis involves the process of translating overarching policy objectives into practical actions within local decision-making practices, abstracting from the intricacies of higher-level policymaking itself. The second objective focuses on the people-policy gap, which involves understanding stakeholders' perspectives and priorities regarding GI and its associated ecosystem services. Through stated preference valuation techniques (discrete choice experiments and a best-worst scaling experiment), multi-stakeholder GI perceptions are gathered. Finally, a novel tool to GI valuation is developed, acknowledging the different stakeholder views and building on the insights of collaborative tool development and design. By gaining insights into the demand, prioritisation, and provision of GI from the two most important stakeholder groups at the local level (residents and local decision-makers), this research aims to foster effective communication and alignment between public preferences and policy implementation. Ultimately, addressing these gaps will contribute to more informed planning and decision-making practices related to green infrastructure. The overall goal of this thesis is to enhance the uptake of GI knowledge in the local decision-making context, proposing pathways to facilitate and optimise investments in public GI. |
| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
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Editor |
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| Language |
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Wos |
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Publication Date |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
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ISBN |
978-90-5728-814-2 |
Additional Links |
UA library record |
| Impact Factor |
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Times cited |
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Open Access |
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| Notes |
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Approved |
Most recent IF: NA |
| Call Number |
UA @ admin @ c:irua:199925 |
Serial |
9206 |
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| Author |
Van Putte, N. |
| Title |
Improving groundwater dynamics : a key factor for successful tidal marsh restoration |
Type |
Doctoral thesis |
| Year |
2023 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
166 p. |
| Keywords |
Doctoral thesis; Sustainable Energy, Air and Water Technology (DuEL); Ecosphere |
| Abstract |
Tidal marshes take up and release certain elements from and to the river water. Hence, they act as a filter, improving the estuarine water quality. This filtering function depends on the interaction between the marsh soil and water that infiltrates into the marsh platform at high tide and seeps out of the creek banks at low tide. In the past centuries, many tidal marshes disappeared due to large scale land reclamations, together with their associated ecosystem services. Nowadays, tidal marshes are increasingly restored on formerly embanked agricultural areas to regain these ecosystem services. Here, we studied the effect of historical agricultural land use on the contribution of restored tidal marshes to water quality improvement, and we investigated several solutions to stimulate the water quality improving function in newly restored tidal marshes. In restored tidal marshes, the soil is often compacted due to the historical agricultural land use, leading to a reduced organic matter content and micro- and macroporosity. In this compacted soil, groundwater flow is hindered, leading to a more waterlogged soil and reduced groundwater dynamics in the restored marsh as compared to a natural marsh. The depth of groundwater drainage and the groundwater flow velocity have important implications for the processes that contribute to water quality improvement, e.g. removal of nitrogen, phosphorus retention and silica cycling. Where groundwater drains deeper, i.e. in the vicinity of tidal creeks and in a more porous soil, these processes are promoted. We suggest that, in newly restored tidal marshes, the soil porosity can be increased by amending the soil (e.g. with organic matter), and the distance to the nearest tidal creek can be reduced by creek excavation. Numerical modelling showed that the largest gain in groundwater dynamics and seepage was attained when both measures were applied together. The effect of organic soil amendments on groundwater dynamics and nutrient cycling was further explored in a large scale in situ mesocosm experiment. Where the soil was amended, groundwater drained deeper and nitrogen removal increased. For new tidal marsh restoration projects, we advise to conduct an explorative soil study. When the soil is heavily compacted, design measures, such as creek initiation and organic soil amendments can be applied to jumpstart the contribution to water quality improvement of newly restored tidal marshes. |
| Address |
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Place of Publication |
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Wos |
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Publication Date |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
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ISBN |
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Additional Links |
UA library record |
| Impact Factor |
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Times cited |
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Open Access |
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| Notes |
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Approved |
Most recent IF: NA |
| Call Number |
UA @ admin @ c:irua:196965 |
Serial |
8884 |
| Permanent link to this record |
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| Author |
van Renterghem, W.; Goessens, C.; Schryvers, D.; van Landuyt, J.; Verrept, P.; Bollen, D.; van Roost, C.; de Keyzer, R. |
| Title |
Defects in AgCl and AgBr(100) tabular crystals studied by TEM |
Type |
P3 Proceeding |
| Year |
1998 |
Publication |
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Abbreviated Journal |
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| Volume |
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Issue |
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Pages |
6-11 |
| Keywords |
P3 Proceeding; Electron microscopy for materials research (EMAT) |
| Abstract |
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| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
Antwerpen |
Editor |
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| Language |
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Wos |
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Publication Date |
0000-00-00 |
| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
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ISBN |
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Additional Links |
UA library record |
| Impact Factor |
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Times cited |
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Open Access |
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| Notes |
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Approved |
Most recent IF: NA |
| Call Number |
UA @ lucian @ c:irua:29680 |
Serial |
628 |
| Permanent link to this record |
