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vanden Berghe, D.; Deelstra, H.; Robberecht, H.; Van Grieken, R. |
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Title |
Selenium content of soils and rye grass (Lolium multiflorum) in Belgium |
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H3 Book chapter |
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1981 |
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85-105
T2 - Mineral elements '80 : part 1 |
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H3 Book chapter; Pharmacology. Therapy; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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no |
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Call Number |
UA @ admin @ c:irua:117483 |
Serial |
8506 |
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Author |
Daems, E. |
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Title |
Shaping up oligonucleotides : aptamer-target recognition investigated by native mass spectrometry |
Type |
Doctoral thesis |
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Year |
2021 |
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235 p. |
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Doctoral thesis; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Abstract |
Aptamers are short, synthetic DNA or RNA molecules that are characterized by a specific 3D conformation which enables specific target recognition. Aptamers are promising tools in many application fields from sensing to therapeutics. One of the major challenges in the aptamer field is understanding the relationship between the sequence and what determines the higher-order structure and specific interactions with targets. Therefore, this PhD thesis focuses on the use of different mass spectrometry (MS) based approaches to characterize aptamers and their interactions. Several of these approaches are already widely applied to study other biomolecules, such as proteins, but are still largely unexplored for aptamers and oligonucleotides in general. A first focus was put on obtaining information on the higher-order structure and conformational stability of aptamers using a combination of MS and with ion mobility (IM) spectrometry by performing collision-induced unfolding (CIU) experiments. CIU was shown to hold great promise to analyze the conformational dynamics and gas-phase stabilities of aptamers. Next, the capabilities and limitations of native IM-MS for the analysis of noncovalent interactions of aptamers were demonstrated. The conformational behavior and interactions of cocaine-binding aptamers were studied and it was found that relative binding affinities of aptamers that only differ slightly in sequence and structure can be determined using native MS. Moreover, native IM-MS allowed the detection of small conformational changes upon binding of a target, which were found to be dependent on the binding mode of the aptamer. An adaptive binding mechanism was suggested for flexible aptamers that require more reorganization upon binding. In the final part of this thesis, the importance of thoroughly characterizing and validating aptamer-target interactions before using them in an application was emphasized. Moreover, the gathered insights were applied in our own development of a proof-of-concept aptamer-based sensor. This was shown by investigating the interactions of ampicillin aptamers which were found to not bind the target they were selected for in the first place. A multi-analytical approach combining complementary techniques was used for this purpose since no single technique is generally applicable to characterize all aptamers and their interactions and to obtain a comprehensive picture of the aptamer-target interactions. Furthermore, such multi-analytical approach was used to characterize a testosterone-binding aptamer while developing an aptamer-based electrochemiluminescent sensing strategy for this target. This shows the importance of native MS, in combination with other techniques, to thoroughly understand the aptamer-target interactions in the development of a designed application. |
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Most recent IF: NA |
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Call Number |
UA @ admin @ c:irua:178116 |
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8517 |
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Author |
Piñera Hernández, I. |
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Title |
Simulation of atom displacements induced by photons and electrons in solids |
Type |
Doctoral thesis |
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Year |
2014 |
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137 p. |
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Doctoral thesis; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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no |
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Call Number |
UA @ admin @ c:irua:116687 |
Serial |
8526 |
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Author |
van Malderen, H.; Van Grieken, R.; Khodzher, T.V.; Grachev, M.; Bufetov, N.S.; Koutsenogii, K.P. |
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Title |
Single particle analysis of aerosols from Siberia |
Type |
P3 Proceeding |
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Year |
1994 |
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Proceedings of the Russian-Ukrainian-Austrian-German Analytical Symposium |
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P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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no |
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Call Number |
UA @ admin @ c:irua:9527 |
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8530 |
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Author |
de Bock, L.A.; Van Grieken, R.E. |
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Title |
Single particle analysis techniques |
Type |
H3 Book chapter |
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Year |
1999 |
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Volume |
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243-275
T2 - Analytical chemistry of aerosols / Sp |
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Keywords |
H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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no |
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Call Number |
UA @ admin @ c:irua:27599 |
Serial |
8534 |
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Author |
Jambers, W.; Van Grieken, R. |
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Title |
Single particle characterisation of inorganic North Sea suspensions |
Type |
P3 Proceeding |
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Year |
1996 |
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P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Call Number |
UA @ admin @ c:irua:14670 |
Serial |
8537 |
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Author |
Kuczumow, A.; Vekemans, B.; Schalm, O.; Vincze, L.; Dorriné, W.; Gysels, K.; Van Grieken, R. |
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Title |
Some new applications of auxiliary signals in X-ray fluorescence and electron microprobe analysis |
Type |
P1 Proceeding |
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Year |
1999 |
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Abbreviated Journal |
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Volume |
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Pages |
197-201
T2 - Proceedings of the European Conferenc |
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Keywords |
P1 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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000081658400032 |
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no |
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Call Number |
UA @ admin @ c:irua:24716 |
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8553 |
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Author |
Van Grieken, R.; Kontozova, V.; Godoi, R.H.M.; Spolnik, Z.; Worobiec, A.; Deutsch, F.; Bencs, L. |
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Title |
Some studies of the effect of indoor and outdoor pollutants on cultural heritage items |
Type |
P3 Proceeding |
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2005 |
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P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Laboratory Experimental Medicine and Pediatrics (LEMP) |
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no |
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Call Number |
UA @ admin @ c:irua:57632 |
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8556 |
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Author |
Török, S.; Szandor, S.; Xhoffer, C.; Van Grieken, R. |
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Title |
Source apportionment of individual aerosol particles at Hungarian background stations |
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H3 Book chapter |
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1993 |
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32-331
T2 - Photo-oxidants: precursors and product |
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H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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no |
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Call Number |
UA @ admin @ c:irua:6265 |
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8559 |
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Author |
Vos, L.; Van Grieken, R. |
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Title |
Spark source mass spectrometry for trace analysis of diverse biological matrices |
Type |
H3 Book chapter |
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Year |
1983 |
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303-306
T2 - Mass spectrometry advances 1982 / Sch |
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H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Call Number |
UA @ admin @ c:irua:117486 |
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8564 |
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Bencs, L.; Ravindra, K.; Van Grieken, R. |
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Spatial and temporal variation of anthropogenic palladium in the environment |
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H3 Book chapter |
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2006 |
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433-454
T2 - Palladium emissions in the environmen |
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H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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UA @ admin @ c:irua:54922 |
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8565 |
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Ravindra, K.; Wauters, E.; Van Grieken, R. |
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Spatial and temporal variations in particulate Polycyclic Aromatic Hydrocarbon (PAH) levels over Menen (Belgium) and their relation with air mass trajectories |
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H3 Book chapter |
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2007 |
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838-841
T2 - Air pollution modeling and its applic |
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H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Call Number |
UA @ admin @ c:irua:65571 |
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8566 |
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Author |
Bruynseels, F.; Van Grieken, R. |
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Title |
Speciation and distribution of sulfur and nitrogen in individual aerosol particles measured by LAMMA |
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P3 Proceeding |
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1984 |
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P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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UA @ admin @ c:irua:117494 |
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8568 |
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Szalóki, I.; Ro, C.-U.; Osán, J.; de Hoog, J.; Van Grieken, R. |
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Speciation and surface analysis of single particles using electron-excited X-ray emission spectrometry |
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2004 |
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569-592
T2 - X-ray spectrometry: recent technologi |
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H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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UA @ admin @ c:irua:43878 |
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8570 |
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Injuk, J.; Van Grieken, R.; Blank, A.; Eksperiandova, L.; Buhrke, V. |
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Specimen preparation |
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2006 |
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411-432
T2 - Handbook of practical X-ray fluoresce |
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H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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UA @ admin @ c:irua:58854 |
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8573 |
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Author |
Playford, K.; Colin, J.L.; Pacyna, J.M.; Pirrone, N.; Schulz, M.; Van Grieken, R.; Wrembel, Z. |
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| |
Title |
State-of-the-art and research needs for trace metals |
Type |
H3 Book chapter |
| |
Year |
1998 |
Publication |
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Abbreviated Journal |
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Volume |
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Issue |
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Pages |
7-11
T2 - Sea-air exchange: processes and modellin |
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Keywords |
H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Open Access |
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Notes |
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Approved |
no |
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Call Number |
UA @ admin @ c:irua:20972 |
Serial |
8580 |
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Author |
Margui, E.; Van Grieken, R. |
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| |
Title |
State-of-the-art X-ray fluorescence instrumentation for chemical analysis |
Type |
A3 Journal article |
| |
Year |
2013 |
Publication |
Petro Industry News |
Abbreviated Journal |
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Volume |
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Issue |
June/July |
Pages |
16-18 |
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Keywords |
A3 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Abstract |
Nowadays, X-ray fluorescence spectrometry (XRF) is a well-established analytical technique for qualitative and quantitative elemental analysis (sometimes from Be to U) of a wide variety of samples. In particular, the truly multi-element character, acceptable speed and economy, ease of automation and the possibility to directly analyse solid samples are the most important features among the many that have made it a very mature analytical tool for routine quality controls in many industries, as well as for analytical support for the research laboratory.e recent technological advances, including the design of low-power micro-focus tubes and the novel X-ray optics and detectors have made it possible to extend XRF to the determination of low-Z elements and to obtain 2D or 3D information on a micrometre-scale. Furthermore, the recent development and commercialisation of benchtop and portable instrumentation, that offer extreme simplicity of operation in a low-cost design, have promoted even more the approach of XRF for many analytical problems.is article highlights this state-of-the art technique with regards to currently available XRF instrumentation on the market as well as recent applications in environmental and industrial fields. |
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Edition |
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ISSN |
1472-0590 |
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UA library record |
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no |
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Call Number |
UA @ admin @ c:irua:109342 |
Serial |
8581 |
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Author |
Van Grieken, R. |
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| |
Title |
Stof : begrippen, bronnen en analysmethoden |
Type |
P3 Proceeding |
| |
Year |
1985 |
Publication |
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Abbreviated Journal |
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Volume |
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Issue |
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Pages |
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Keywords |
P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Approved |
no |
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| |
Call Number |
UA @ admin @ c:irua:117501 |
Serial |
8582 |
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| |
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Author |
Injuk, J.; de Bock, L.; Van Grieken, R. |
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| |
Title |
Structural heterogeneity within airborne particles |
Type |
H3 Book chapter |
| |
Year |
1998 |
Publication |
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Abbreviated Journal |
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| |
Volume |
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Issue |
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Pages |
173-202
T2 - Atmospheric particles / Harrison, R.M |
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Keywords |
H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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UA library record |
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Open Access |
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Notes |
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Approved |
no |
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| |
Call Number |
UA @ admin @ c:irua:20969 |
Serial |
8586 |
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Author |
Samek, L.; Worobiec, A.; Spolnik, Z.; Van Grieken, R. |
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| |
Title |
Studia sezonowych zmian wewnetrznego składu powietrza atmosferycznego w kościołach zabytkowych w kontekście doboru i modyfikacji metod konserwacji obiektów zabytkowych |
Type |
H3 Book chapter |
| |
Year |
2005 |
Publication |
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Abbreviated Journal |
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| |
Volume |
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Issue |
|
Pages |
59-64
T2 - Technika jadrowa w przemyśle, medycynie |
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| |
Keywords |
H3 Book chapter; Laboratory Experimental Medicine and Pediatrics (LEMP); AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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UA library record |
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Notes |
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Approved |
no |
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| |
Call Number |
UA @ admin @ c:irua:53886 |
Serial |
8591 |
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Author |
Cholewa, M.; Legge, G.J.F.; Eeckhaoudt, S.; Van Grieken, R. |
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| |
Title |
A study of aluminium-exposed fish using a scanning proton microprobe |
Type |
P3 Proceeding |
| |
Year |
1994 |
Publication |
Proceedings of the Australian Conference on Nuclear Techniques of Analysis |
Abbreviated Journal |
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Volume |
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Issue |
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Pages |
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Keywords |
P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Additional Links |
UA library record |
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Open Access |
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Notes |
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Approved |
no |
|
| |
Call Number |
UA @ admin @ c:irua:9517 |
Serial |
8594 |
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| Permanent link to this record |
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Author |
Zezza, F.; Torfs, K.; Van Grieken, R.; García Pascua, N.; Macri, F. |
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| |
Title |
Study of environmental effects on deterioration of monuments: case study the cathedral of Bari, Italy |
Type |
P3 Proceeding |
| |
Year |
1996 |
Publication |
|
Abbreviated Journal |
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Volume |
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Issue |
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Pages |
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Keywords |
P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Abstract |
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Wos |
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| |
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Edition |
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|
| |
ISSN |
|
ISBN |
|
Additional Links |
UA library record |
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| |
Impact Factor |
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Open Access |
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|
| |
Notes |
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Approved |
no |
|
| |
Call Number |
UA @ admin @ c:irua:14665 |
Serial |
8597 |
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| Permanent link to this record |
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| |
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Author |
Bernard, P.; Van Grieken, R.; Eisma, D. |
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| |
Title |
Study of individual estuarine suspension particles by automated electron-probe X-ray microanalysis |
Type |
P3 Proceeding |
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Year |
1985 |
Publication |
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Abbreviated Journal |
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Volume |
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Issue |
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Pages |
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Keywords |
P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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| |
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ISBN |
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Additional Links |
UA library record |
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| |
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Open Access |
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|
| |
Notes |
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Approved |
no |
|
| |
Call Number |
UA @ admin @ c:irua:117498 |
Serial |
8598 |
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| Permanent link to this record |
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| |
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Author |
Van Grieken, R.; Injuk, J.; de Bock, L.; van Malderen, H. |
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| |
Title |
Study of individual particle types and heavy metal deposition for North Sea aerosols using micro and trace analysis techniques |
Type |
H3 Book chapter |
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Year |
2000 |
Publication |
|
Abbreviated Journal |
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Volume |
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Issue |
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Pages |
105-110
T2 - Exchange and transport of air polluta |
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Keywords |
H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Notes |
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Approved |
no |
|
| |
Call Number |
UA @ admin @ c:irua:31676 |
Serial |
8599 |
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| Permanent link to this record |
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| |
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Author |
Injuk, J.; de Bock, L.; van Malderen, H.; Van Grieken, R. |
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| |
Title |
Study of individual particle types and heavy metal deposition for North Sea aerosols using micro- and trace analysis techniques |
Type |
P3 Proceeding |
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Year |
1996 |
Publication |
|
Abbreviated Journal |
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Volume |
|
Issue |
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Pages |
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Keywords |
P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Notes |
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Approved |
no |
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| |
Call Number |
UA @ admin @ c:irua:14682 |
Serial |
8600 |
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| Permanent link to this record |
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Author |
Jones, K.W.; Feng, H.; Lindquist, W.B.; Adler, P.M.; Thover, J.F.; Vekemans, B.; Vincze, L.; Szalóki, I.; Van Grieken, R.; Adams, F.; Riekel, C. |
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| |
Title |
Study of microgeometry of porous materials using synchrotron computed microtomography |
Type |
H3 Book chapter |
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Year |
2003 |
Publication |
|
Abbreviated Journal |
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Volume |
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Issue |
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Pages |
39-49
T2 - Applications of X-ray computed tomograp |
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Keywords |
H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Additional Links |
UA library record |
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Impact Factor |
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Open Access |
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|
| |
Notes |
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Approved |
no |
|
| |
Call Number |
UA @ admin @ c:irua:41596 |
Serial |
8602 |
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| Permanent link to this record |
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| |
|
Author |
Injuk, J.; van Malderen, H.; Van Grieken, R. |
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| |
Title |
Study of the heavy metal concentration, deposition and sources of the North Sea aerosols using X-ray emission techniques |
Type |
H3 Book chapter |
| |
Year |
1993 |
Publication |
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Abbreviated Journal |
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| |
Volume |
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Issue |
|
Pages |
793-795
T2 - Photo-oxidants: precursors and produc |
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Keywords |
H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Abstract |
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| |
Notes |
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Approved |
no |
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| |
Call Number |
UA @ admin @ c:irua:6266 |
Serial |
8605 |
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| Permanent link to this record |
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Author |
Leyva Pernia, D.; Cabal Rodríguez, A.E.; Schalm, O.; van Espen, P.; Piñera Hernández, I.; Abreu Alfonso, Y. |
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| |
Title |
Study of the main physical processes contributing to image formation in emission radiography using mathematical modeling |
Type |
P3 Proceeding |
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Year |
2013 |
Publication |
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Abbreviated Journal |
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Volume |
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Issue |
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Pages |
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Keywords |
P3 Proceeding; Engineering sciences. Technology; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Antwerp Cultural Heritage Sciences (ARCHES) |
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ISSN |
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ISBN |
978-959-7136-98-9 |
Additional Links |
UA library record |
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Notes |
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Approved |
no |
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| |
Call Number |
UA @ admin @ c:irua:135412 |
Serial |
8607 |
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| Permanent link to this record |
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Author |
Treiger, B.; Bondarenko, I.; van Malderen, H.; Van Grieken, R. |
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| |
Title |
Studying the composition of atmospheric aerosols through the joint application of hierarchical, non-hierarchical and fuzzy clustering to EPXMA data sets |
Type |
P3 Proceeding |
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Year |
1996 |
Publication |
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Abbreviated Journal |
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Volume |
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Issue |
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Pages |
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Keywords |
P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Edition |
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ISSN |
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ISBN |
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Additional Links |
UA library record |
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|
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Notes |
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Approved |
no |
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| |
Call Number |
UA @ admin @ c:irua:14661 |
Serial |
8611 |
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| Permanent link to this record |
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Author |
Joos, P.E.; Godoi, A.F.L.; de Jong, R.; de Zeeuw, J.; Van Grieken, R. |
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| |
Title |
Sub-minute determination of BTEX in environmental samples using low pressure GC-ITMS |
Type |
P3 Proceeding |
| |
Year |
2002 |
Publication |
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Abbreviated Journal |
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Volume |
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Issue |
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Pages |
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Keywords |
P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Abstract |
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Edition |
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Additional Links |
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Impact Factor |
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|
| |
Notes |
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Approved |
no |
|
| |
Call Number |
UA @ admin @ c:irua:38153 |
Serial |
8612 |
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| Permanent link to this record |
