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Author Shani, J.; Livshitz, T.; Robberecht, H.; Van Grieken, R.; Rubinstein, N.; Even-Paz, Z.
Title Increased erythrocyte glutathione peroxidase activity in psoriatics consuming high-selenium drinking water at the dead-sea psoriasis treatment center Type A3 Journal article
Year (down) 1985 Publication Pharmacological research communications Abbreviated Journal
Volume 17 Issue 5 Pages 479-488
Keywords A3 Journal article; Pharmacology. Therapy; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract Erythrocyte selenium-dependent glutathione peroxidase activity was measured in psoriatic Danes, before and after their four-week balneological therapy at the Ein-Bokek International Psoriasis Treatment Center, on the Dead-Sea shore in Israel. The drinking water in Ein-Bokek was found to be rich in selenium, a trace element with anticarcinogenic properties and of great importance in human nutrition and health. The most reliable biological parameter for increase in selenium bioavailability is the erythrocytes' glutathione-peroxidase activity. As psoriasis is a proliferative skin disease, the activity of this enzyme was assayed in 35 psoriatic Danes and in 25 long-term local hotel workers, as well as in 34 volunteers drinking low-selenium water. The glutathione peroxidase activity in the psoriatic patients increased significantly during their four-week stay in Ein-Bokek. Erythrocyte glutathione peroxidase activity in the hotel workers was 50% higher than that in the healthy volunteers consuming low-selenium water. A possible role of selenium in psoriasis is suggested.
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Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date 2004-10-04
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-6989 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116758 Serial 8076
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