%&LaTeX
\documentclass{article}

\usepackage[utf8]{inputenc}
\usepackage[T1]{fontenc}
\usepackage{textcomp}

\begin{document}

\begin{thebibliography}{1}

\bibitem{Han_etal2016} {\textquotedblleft}\textit{Uncoupling the solids retention times of flocs and granules in mainstream deammonification : a screen as effective out-selection tool for nitrite oxidizing bacteria}{\textquotedblright}. Han M, Vlaeminck SE, Al-Omari A, Wett B, Bott C, Murthy S, De Clippeleir H, Bioresource technology \textbf{221}, 195 (2016).   http://doi.org/10.1016/J.BIORTECH.2016.08.115

\end{thebibliography}

\end{document}

