%&LaTeX
\documentclass{article}

\usepackage[utf8]{inputenc}
\usepackage[T1]{fontenc}
\usepackage{textcomp}

\begin{document}

\begin{thebibliography}{1}

\bibitem{Tsai_etal2016} {\textquotedblleft}\textit{Hollow Cone Electron Imaging for Single Particle 3D Reconstruction of Proteins}{\textquotedblright}. Tsai C-Y, Chang Y-C, Lobato I, Van Dyck D, Chen F-R, Scientific reports \textbf{6}, 27701 (2016).   http://doi.org/10.1038/srep27701

\end{thebibliography}

\end{document}

