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| Author | Vandeputte, D.; Van Grieken, R.E.; Jacob, W.A.; Savory, J.; Bertholf, R.L.; Wills, M.R. | ||||
| Title | Ultrastructural localization of aluminium in liver of aluminium maltol-treated rabbits by laser microprobe mass analysis | Type | A1 Journal article | ||
| Year | 1989 | Publication | Biomedical and environmental mass spectrometry | Abbreviated Journal | |
| Volume | 18 | Issue | 8 | Pages | 598-602 |
| Keywords | A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) | ||||
| Abstract | By means of laser microprobe mass analysis (LAMMA), we have studied the ultrastructural localization of aluminium in livers of aluminium maltol-treated rabbits. This animal model was developed to study long-term aluminium toxicity using systemic (intravenous) administration of aluminium. We could only detect aluminium in electron-dense inclusion bodies found in large, sometimes multinucleated cells. These results prove that the actual observation of aluminium deposits in liver with LAMMA gives more information than bulk analysis and can be very useful to explore mechanisms of toxicity. | ||||
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| Language | Wos  |
Publication Date | 2005-05-29 | ||
| Series Editor | Series Title | Abbreviated Series Title | |||
| Series Volume | Series Issue | Edition | |||
| ISSN | 0887-6134 | ISBN | Additional Links | UA library record | |
| Impact Factor | Times cited | Open Access | |||
| Notes | Approved | no | |||
| Call Number | UA @ admin @ c:irua:116817 | Serial | 8702 | ||
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