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Author Cuypers, B.; Vermeylen, S.; Hammerschmid, D.; Trashin, S.; Rahemi, V.; Konijnenberg, A.; De Schutter, A.; Cheng, C.-H.C.; Giordano, D.; Verde, C.; De Wael, K.; Sobott, F.; Dewilde, S.; Van Doorslaer, S.
Title (up) Antarctic fish versus human cytoglobins : the same but yet so different Type A1 Journal article
Year 2017 Publication Journal of inorganic biochemistry Abbreviated Journal J Inorg Biochem
Volume 173 Issue Pages 66-78
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract The cytoglobins of the Antarctic fish Chaenocephalus aceratus and Dissostichus mawsoni have many features in common with human cytoglobin. These cytoglobins are heme proteins in which the ferric and ferrous forms have a characteristic hexacoordination of the heme iron, i.e. axial ligation of two endogenous histidine residues, as confirmed by electron paramagnetic resonance, resonance Raman and optical absorption spectroscopy. The combined spectroscopic analysis revealed only small variations in the heme-pocket structure, in line with the small variations observed for the redox potential. Nevertheless, some striking differences were also discovered. Resonance Raman spectroscopy showed that the stabilization of an exogenous heme ligand, such as CO, occurs differently in human cytoglobin in comparison with Antarctic fish cytoglobins. Furthermore, while it has been extensively reported that human cytoglobin is essentially monomeric and can form an intramolecular disulfide bridge that can influence the ligand binding kinetics, 3D modeling of the Antarctic fish cytoglobins indicates that the cysteine residues are too far apart to form such an intramolecular bridge. Moreover, gel filtration and mass spectrometry reveal the occurrence of non-covalent multimers (up to pentamers) in the Antarctic fish cytoglobins that are formed at low concentrations. Stabilization of these oligomers by disulfide-bridge formation is possible, but not essential. If intermolecular disulfide bridges are formed, they influence the heme-pocket structure, as is shown by EPR measurements.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000405159600007 Publication Date 2017-04-28
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0162-0134 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor 3.348 Times cited 7 Open Access
Notes ; The authors acknowledge the support of the University of Antwerp GOA-BOF funding (28312), FWO funding (G.0687.13) and the Hercules foundation for funding of the Synapt G2 instrument. This study was carried out in the framework of the SCAR program “Antarctic Thresholds – Ecosystem Resilience and Adaptation” (AnT-ERA). It was financially supported by the Italian National Program for Antarctic Research (PNRA). Research of A. De Schutter is funded by a PhD grant of the Agency for Innovation by Science and Technology (121339) (IWT, Belgium). C-H C. Cheng acknowledges funding support from US National Science Foundation Polar Programs (ANT-1142158). ; Approved Most recent IF: 3.348
Call Number UA @ admin @ c:irua:144826 Serial 5474
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Author Gijbels, R.; van Grieken, R.
Title (up) Application of analytical methods for trace elements in geothermal waters : part 1 : Amélie-les-Bains (Eastern Pyrenees) Type MA3 Book as author
Year 1977 Publication Abbreviated Journal
Volume Issue Pages
Keywords MA3 Book as author; Plasma Lab for Applications in Sustainability and Medicine – Antwerp (PLASMANT); AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication S.l. Editor
Language Wos Publication Date 0000-00-00
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ lucian @ c:irua:117471 Serial 139
Permanent link to this record
 

 
Author Gijbels, R.; van Grieken, R.; Blommaert, W.; Van 't dack, L.; van Espen, P.; Nullens, H.; Saelens, R.
Title (up) Application of analytical methods for trace elements in geothermal waters : part 2 : Plombières, Bains-les-Bains, Bourbonne (Vosges) Type MA3 Book as author
Year 1983 Publication Abbreviated Journal
Volume Issue Pages
Keywords MA3 Book as author; Plasma Lab for Applications in Sustainability and Medicine – Antwerp (PLASMANT); AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Chemometrics (Mitac 3)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication S.l. Editor
Language Wos Publication Date 0000-00-00
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ lucian @ c:irua:117472 Serial 140
Permanent link to this record
 

 
Author Kuczumov, A.; Vekemans, B.; Schalm, O.; Vincze, L.; Dorriné, W.; Gysels, K.; Van Grieken, R.
Title (up) Application of auxiliary signals in X-ray fluorescence and electron microprobe analysis for density evaluation Type A1 Journal article
Year 1999 Publication X-ray spectrometry Abbreviated Journal
Volume 28 Issue Pages 282-291
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000081693400014 Publication Date 2002-09-10
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0049-8246 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:27584 Serial 7467
Permanent link to this record
 

 
Author Osán, J.; de Hoog, J.; Worobiec, A.; Ro, C.-U.; Oh, K.-Y.; Szalóki, I.; Van Grieken, R.
Title (up) Application of chemometric methods for classification of atmospheric particles based on thin-window electron probe microanalysis data Type A1 Journal article
Year 2001 Publication Analytica chimica acta Abbreviated Journal
Volume 446 Issue Pages 211-222
Keywords A1 Journal article; Laboratory Experimental Medicine and Pediatrics (LEMP); AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000172309400020 Publication Date
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0003-2670; 1873-4324 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:36385 Serial 7468
Permanent link to this record
 

 
Author Uzonyi, I.; Szöör, G.; Vekemans, B.; Vincze, L.; Rozsa, P.; Szabo, G.; Somogyi, A.; Adams, F.; Kiss, Á.Z.
Title (up) Application of combined micro-proton-induced X-ray emission and micro-synchrotron radiation X-ray fluorescence techniques for the characterization of impact materials around Barringer Meteor Crater Type A1 Journal article
Year 2004 Publication Spectrochimica acta: part B : atomic spectroscopy Abbreviated Journal
Volume 59 Issue Pages 1717-1723
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000224848000031 Publication Date 2004-09-14
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0584-8547; 1873-3565 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:49638 Serial 7469
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Author de Maeyer-Worobiec, A.; Stefaniak, E.A.; Brooker, A.; Van Grieken, R.
Title (up) Application of combined SEM/EDX and μ-Raman approaches for the chemical and structural characterisation of fine particulates Type P3 Proceeding
Year 2007 Publication Abbreviated Journal
Volume Issue Pages
Keywords P3 Proceeding; Laboratory Experimental Medicine and Pediatrics (LEMP); AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:64633 Serial 7470
Permanent link to this record
 

 
Author Spolnik, Z.; Bencs, L.; Worobiec, A.; Kontozova, V.; Van Grieken, R.
Title (up) Application of EDXRF and thin window EPMA for the investigation of the influence of hot air heating on the generation and deposition of particulate matter Type A1 Journal article
Year 2005 Publication Microchimica acta Abbreviated Journal
Volume 149 Issue Pages 79-85
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Laboratory Experimental Medicine and Pediatrics (LEMP)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000226408200010 Publication Date 2005-01-18
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:51258 Serial 7471
Permanent link to this record
 

 
Author Xhoffer, C.; Jacob, W.; Van Grieken, R.
Title (up) Application of electron energy loss spectroscopy to aerosols Type A1 Journal article
Year 1989 Publication Journal of aerosol science Abbreviated Journal
Volume 20 Issue 8 Pages 1617-1619
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos A1989CN23100191 Publication Date 2003-08-06
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0021-8502; 1879-1964 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116820 Serial 7472
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Author Szalóki, I.; Varga, K.; Van Grieken, R.
Title (up) Application of energy dispersive X-ray spectrometry for quantitative evaluation of sorption phenomena at solid-liquid interfaces Type A1 Journal article
Year 2000 Publication Spectrochimica acta: part B : atomic spectroscopy Abbreviated Journal
Volume 55 Issue Pages 1031-1038
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000088353100032 Publication Date 2002-07-25
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0584-8547; 1873-3565 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:32124 Serial 7473
Permanent link to this record
 

 
Author Kontozova-Deutsch, V.; Deutsch, F.; Godoi, R.H.M.; Spolnik, Z.; Wei, W.; Van Grieken, R.
Title (up) Application of EPMA and XRF for the investigation of particulate pollutants in the field of cultural heritage Type A1 Journal article
Year 2008 Publication Microchimica acta Abbreviated Journal
Volume 161 Issue 3/4 Pages 465-469
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000256175600029 Publication Date 2008-01-30
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0026-3672; 1436-5073 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:68798 Serial 7474
Permanent link to this record
 

 
Author van Meel, K.; Fontàs, C.; Van Grieken, R.; Queralt, I.; Hidalgo, M.; Marguí, E.
Title (up) Application of high-energy polarised beam energy dispersive X-ray fluorescence spectrometry to cadmium determination in saline solutions Type A1 Journal article
Year 2008 Publication Journal of analytical atomic spectrometry Abbreviated Journal
Volume 23 Issue 7 Pages 1034-1037
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000257146000017 Publication Date 2008-04-22
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0267-9477 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:69424 Serial 7476
Permanent link to this record
 

 
Author Verbueken, A.H.; Van de Vyver, F.L.; Visser, W.J.; de Broe, M.E.; Van Grieken, R.E.
Title (up) Application of laser microprobe mass analysis (LAMMA) to problems in nephrology Type H3 Book chapter
Year 1986 Publication Abbreviated Journal
Volume Issue Pages 987-988 T2 - Advances in mass spectrometry 1985/ T
Keywords H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Laboratory Experimental Medicine and Pediatrics (LEMP)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:117505 Serial 7478
Permanent link to this record
 

 
Author Bekshaev, A.; Kontush, S.; Popov, A.; Van Grieken, R.
Title (up) Application of light beams with non-zero angular momentum in optical study of micrometer-size aerosol particles Type P1 Proceeding
Year 2001 Publication Abbreviated Journal
Volume Issue Pages 288-296 T2 - Second International Conference on Si
Keywords P1 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000171469300037 Publication Date 2003-11-19
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:36386 Serial 7479
Permanent link to this record
 

 
Author Godoi, A.F.L.; Vilegas, W.; Godoi, R.H.M.; Van Vaeck, L.; Van Grieken, R.
Title (up) Application of low-pressure gas chromatography-io-trap mass spectrometry to the analysis of the eseential oil of Turnera diffusa (Ward.) Urb Type A1 Journal article
Year 2004 Publication Journal of chromatography: A: bibliography section Abbreviated Journal
Volume 1027 Issue Pages 127-130
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000188498900018 Publication Date 2003-10-14
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:43529 Serial 7480
Permanent link to this record
 

 
Author Akselsson, R.; Orsini, C.; Meinert, D.L.; Johansson, T.B.; Van Grieken, R.E.; Kaufmann, H.C.; Chapman, K.R.; Nelson, J.W.; Winchester, J.W.
Title (up) Application of proton induced X-ray emission analysis to the St. Louis regional air pollution study Type P3 Proceeding
Year 1976 Publication Abbreviated Journal
Volume Issue Pages
Keywords P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:113633 Serial 7481
Permanent link to this record
 

 
Author Osán, J.; Kurunczi, S.; Török, S.; Worobiec, A.; Van Grieken, R.
Title (up) Application of thin-window EPMA to environmental problems in Hungary Type A1 Journal article
Year 2002 Publication Microchimica acta Abbreviated Journal
Volume 139 Issue Pages 111-117
Keywords A1 Journal article; Laboratory Experimental Medicine and Pediatrics (LEMP); AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000175560300017 Publication Date 2003-03-05
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0026-3672; 1436-5073 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:39521 Serial 7484
Permanent link to this record
 

 
Author Gijbels, R.; van Grieken, R.; Blommaert, W.; Vandelannoote, R.; Van 't dack, L.
Title (up) Application of trace element analysis to geothermal waters Type P3 Proceeding
Year 1977 Publication Abbreviated Journal
Volume Issue Pages 429-439
Keywords P3 Proceeding; Plasma Lab for Applications in Sustainability and Medicine – Antwerp (PLASMANT); AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Directorate General for Research, Science and Education Place of Publication Brussels Editor
Language Wos Publication Date 0000-00-00
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ lucian @ c:irua:117462 Serial 143
Permanent link to this record
 

 
Author Janssens, K.; Adams, F.
Title (up) Applications in art and archaeology Type H3 Book chapter
Year 2000 Publication Abbreviated Journal
Volume Issue Pages 290-313
Keywords H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved Most recent IF: NA
Call Number UA @ admin @ c:irua:27579 Serial 5475
Permanent link to this record
 

 
Author Verbueken, A.H.; van de Vijver, F.L.; de Broe, M.E.; Van Grieken, R.E.
Title (up) Applications of laser microprobe mass analysis in medicine Type A3 Journal article
Year 1987 Publication CRC critical reviews in clinical laboratory sciences Abbreviated Journal
Volume 24 Issue Pages 263-285
Keywords A3 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Laboratory Experimental Medicine and Pediatrics (LEMP)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0590-8191 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116775 Serial 7485
Permanent link to this record
 

 
Author Jambers, W.; de Bock, L.; Van Grieken, R.
Title (up) Applications of micro-analysis to individual environmental particles Type A1 Journal article
Year 1996 Publication Fresenius' journal of analytical chemistry Abbreviated Journal
Volume 355 Issue Pages 521-527
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos A1996UV61000015 Publication Date 2004-03-24
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0937-0633; 1432-1130 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:14653 Serial 7486
Permanent link to this record
 

 
Author Cotte, M.; Genty-Vincent, A.; Janssens, K.; Susini, J.
Title (up) Applications of synchrotron X-ray nano-probes in the field of cultural heritage Type A1 Journal article
Year 2018 Publication Comptes rendus : physique Abbreviated Journal Cr Phys
Volume 19 Issue 7 Pages 575-588
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract Synchrotron-based techniques are increasingly used in the field of cultural heritage, and this review focuses notably on the application of nano-beams to access high-spatial-resolution information on fragments sampled in historical or model artworks. Depending on the targeted information, various nano-analytical techniques can be applied, providing both identification and localization of the various components. More precisely, nano-X-ray fluorescence probes elements, nano-X-ray diffraction identify crystalline phases, and nano X-ray absorption spectroscopy is sensitive to speciation. Furthermore, computed tomography-based techniques can provide useful information about the morphology and in particular the porosity of materials. (C) 2018 Academie des sciences. Published by Elsevier Masson SAS.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000451631400006 Publication Date 2018-08-13
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1631-0705; 1878-1535 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor 2.048 Times cited 3 Open Access
Notes ; ; Approved Most recent IF: 2.048
Call Number UA @ admin @ c:irua:156320 Serial 5476
Permanent link to this record
 

 
Author Cardell, C.; Yebra, A.; Van Grieken, R.E.
Title (up) Applying digital image processing to SEM-EDX and BSE images to determine and quantify porosity and salts with depth in porous media Type A1 Journal article
Year 2002 Publication Microchimica acta Abbreviated Journal
Volume 140 Issue Pages 9-14
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000178757500003 Publication Date 2003-03-05
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:40619 Serial 7487
Permanent link to this record
 

 
Author Bencs, L.; Ravindra, K.; de Hoog, J.; Spolnik, Z.; Bleux, N.; Berghmans, P.; Deutsch, F.; Roekens, E.; Van Grieken, R.
Title (up) Appraisal of measurement methods, chemical composition and sources of fine atmospheric particles over six different areas of Northern Belgium Type A1 Journal article
Year 2010 Publication Environmental pollution Abbreviated Journal
Volume 158 Issue 11 Pages 3421-3430
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract Daily and seasonal variation in the total elemental, organic carbon (OC) and elemental carbon (EC) content and mass of PM2.5 were studied at industrial, urban, suburban and agricultural/rural areas. Continuous (optical Dustscan, standard tapered element oscillating micro-balance (TEOM), TEOM with filter dynamics measurement system), semi-continuous (Partisol filter-sampling) and non-continuous (Dekati-impactor sampling and gravimetry) methods of PM2.5 mass monitoring were critically evaluated. The average elemental fraction accounted for 26% of the PM2.5 mass measured by gravimetry. Metals, like K, Mn, Fe, Cu, Zn and Pb were strongly inter-correlated, also frequently with non-metallic elements (P, S, Cl and/or Br) and EC/OC. A high OC/EC ratio (29) was generally observed. The total carbon content of PM2.5 ranged between 3 and 77% (averages: 1232%), peaking near industrial/heavy trafficked sites. Principal component analysis identified heavy oil burning, ferrous/non-ferrous industry and vehicular emissions as the main sources of metal pollution. This work compares various aerosol monitoring methods to characterize PM2.5 over six locations of different anthropogenic activities over Northern Belgium.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000282563200009 Publication Date 2010-08-23
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0269-7491; 1873-6424 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:84237 Serial 7488
Permanent link to this record
 

 
Author Daems, E.; Dewaele, D.; Barylyuk, K.; De Wael, K.; Sobott, F.
Title (up) Aptamer-ligand recognition studied by native ion mobility-mass spectrometry Type A1 Journal article
Year 2021 Publication Talanta Abbreviated Journal Talanta
Volume 224 Issue Pages 121917
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract The range of applications for aptamers, small oligonucleotide-based receptors binding to their targets with high specificity and affinity, has been steadily expanding. Our understanding of the mechanisms governing aptamer-ligand recognition and binding is however lagging, stymieing the progress in the rational design of new aptamers and optimization of the known ones. Here we demonstrate the capabilities and limitations of native ion mobility-mass spectrometry for the analysis of their higher-order structure and non-covalent interactions. A set of related cocaine-binding aptamers, displaying a range of folding properties and ligand binding affinities, was used as a case study in both positive and negative electrospray ionization modes. Using carefully controlled experimental conditions, we probed their conformational behavior and interactions with the high-affinity ligand quinine as a surrogate for cocaine. The ratios of bound and unbound aptamers in the mass spectra were used to rank them according to their apparent quinine-binding affinity, qualitatively matching the published ranking order. The arrival time differences between the free aptamer and aptamer-quinine complexes were consistent with a small ligand-induced conformational change, and found to inversely correlate with the affinity of binding. This mass spectrometry-based approach provides a fast and convenient way to study the molecular basis of aptamer-ligand recognition.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000600787800122 Publication Date 2020-12-02
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0039-9140; 1873-3573 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor 4.162 Times cited Open Access OpenAccess
Notes Approved Most recent IF: 4.162
Call Number UA @ admin @ c:irua:174086 Serial 7490
Permanent link to this record
 

 
Author Stefan, G.; Hosu, O.; De Wael, K.; Jesus Lobo-Castanon, M.; Cristea, C.
Title (up) Aptamers in biomedicine : selection strategies and recent advances Type A1 Journal article
Year 2021 Publication Electrochimica Acta Abbreviated Journal Electrochim Acta
Volume 376 Issue Pages 137994
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract Aptamers have come in the spotlight as bio-mimetic molecular recognition elements in the field of biomedicine due to various applications in diagnostics, drug delivery, therapeutics, and pharmaceutical analysis. Aptamers are composed of nucleic acid strands (DNA or RNA) that can specifically interact in a three-dimensional tailored design with the target molecule. The basic method to generate aptamers is Systematic Evolution of Ligands by Exponential Enrichment (SELEX). Recent technological advances in aptamer selection allow for faster and cheaper production of a new generation of high-affinity aptamers compared to the traditional SELEX, which can last up to several months. Rigorous characterization performed by multiple research groups endorsed several well-defined aptamer sequences. Binding affinity, nature of the biomolecular interactions and structural characterization are of paramount importance for aptamer screening and development of applications. However, remarkable challenges still need to be dealt with before the aptamers can make great contributions to the biomedical field. Poor specificity and sensitivity, questionable clinical use, low drug loading, in vivo stability and toxicity are only some of the identified challenges. This review accounts for the 30th celebration of the SELEX technology underlining the most important aptamers' achievements in the biomedical field within mostly the past five years. Aptamers' advantages over antibodies are discussed. Because of potential clinical translational utility, insights of remarkable developments in aptamer-based methods for diagnosis and monitoring of disease biomarkers and pharmaceuticals are discussed focusing on the recent studies (2015-2020). The current challenges and promising opportunities for aptamers for therapeutic and theragnostic purposes are also presented. (C) 2021 Elsevier Ltd. All rights reserved.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000634761900003 Publication Date 2021-02-22
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0013-4686 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor 4.798 Times cited Open Access Not_Open_Access
Notes Approved Most recent IF: 4.798
Call Number UA @ admin @ c:irua:177677 Serial 7491
Permanent link to this record
 

 
Author Pilehvar, S.; Mehta, J.; Dardenne, F.; Robbens, J.; Blust, R.; De Wael, K.
Title (up) Aptasensing of chloramphenicol in the presence of its analogues : reaching the maximum residue limit Type A1 Journal article
Year 2012 Publication Analytical chemistry Abbreviated Journal Anal Chem
Volume 84 Issue 15 Pages 6753-6758
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract A novel label-free folding induced aptamer-based electrochemical biosensor for the detection of chloramphenicol (CAP) in the presence of its analogues has been developed. CAP is a broad-spectrum antibiotic which has lost its favor due to its serious adverse toxic effects on human health. Aptamers are artificial nucleic acid ligands (ssDNA or RNA) able to specifically recognize a target such as CAP. In this article, the aptamers are fixed onto a gold electrode surface by a self-assembly approach. In the presence of CAP, the unfolded ssDNA on the electrode surface changes to a hairpin structure bringing the target molecules close to the surface and trigger electron transfer. Detection limits were determined to be 1.6×10-9 mol L-1. In addition, thiamphenicol (TAP) and florfenicol (FF), antibiotics with a similar structure to CAP, did not influence the performance of the aptasensor, suggesting a good selectivity of the CAP-aptasensor. Simplicity and lower detection limit (because of the home-selected aptamers) make that the electrochemical aptasensor is suitable for practical use in the detection of CAP in milk samples.
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Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000307159200069 Publication Date 2012-06-20
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0003-2700; 5206-882x ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor 6.32 Times cited 68 Open Access
Notes ; ; Approved Most recent IF: 6.32; 2012 IF: 5.695
Call Number UA @ admin @ c:irua:98816 Serial 5477
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Author Darchuk, L.; Tsybrii, Z.; Worobiec, A.; Vázquez, C.; Palacios, O.M.; Stefaniak, E.A.; Gatto Rotondo, G.; Sizov, F.; Van Grieken, R.
Title (up) Argentinean prehistoric pigments' study by combined SEM/EDX and molecular spectroscopy Type A1 Journal article
Year 2010 Publication Spectrochimica acta: part A: molecular and biomolecular spectroscopy Abbreviated Journal
Volume 75 Issue 5 Pages 1398-1402
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Laboratory Experimental Medicine and Pediatrics (LEMP)
Abstract Composition of the prehistoric pigments (from Carriqueo rock shelter, Rio Negro province, Argentina) has been analysed by means of molecular spectroscopy (Fourier transform infrared (FTIR) and micro-Raman) and scanning electron microscopy (SEM) coupled to an energy-dispersive X-ray spectrometer (EDS). Red and yellow pigments were recognized as red and yellow ochre. The matrix of the pigments is composed of one or more substances. According to the matrix composition yellow and red pigments were also divided into two groupsi.e. those containing kaolinite or sulphates. Green pigment was detected as green earth, made up of celadonite as a chromophore.
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Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000277231700004 Publication Date 2010-02-05
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1386-1425 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:81939 Serial 7493
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Author Van Grieken, R.; Janssens, K.; Van 't dack, L.; Meersman, G.
Title (up) Art 2002 : 7th International Conference on Non-destructive Testing and Microanalysisfor the Diagnostics and Conservation of the Cultural and Environmental Heritage, 2-6 June 2002, Congress Centre Elzenveld, Antwerp, Belgium Type ME3 Book as editor
Year 2002 Publication Abbreviated Journal
Volume Issue Pages 780 p.
Keywords ME3 Book as editor; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
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Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved Most recent IF: NA
Call Number UA @ admin @ c:irua:39523 Serial 5478
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Author van Loon, A.; Noble, P.; Krekeler, A.; van der Snickt, G.; Janssens, K.; Abe, Y.; Nakai, I.; Dik, J.
Title (up) Artificial orpiment, a new pigment in Rembrandt's palette Type A1 Journal article
Year 2017 Publication Heritage science Abbreviated Journal
Volume 5 Issue Pages 26
Keywords A1 Journal article; Art; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract This paper reports on how the application of macro X-ray fluorescence (MA-XRF) imaging, in combination with the re-examination of existing paint cross-sections, has led to the discovery of a new pigment in Rembrandt's palette: artificial orpiment. In the NWO Science4Arts 'ReVisRembrandt' project, novel chemical imaging techniques are being developed and applied to the study of Rembrandt's late paintings in order to help resolve outstanding questions and to gain a better understanding of his late enigmatic painting technique. One of the selected case studies is the Portrait of a Couple as Isaac and Rebecca, known as 'The Jewish Bride', dated c. 1665 and on view in the Rijksmuseum. During the re-installation of the Rijksmuseum in 2013, the picture was scanned using the Bruker M6 Jetstream MAXRF scanner. The resulting elemental distribution maps made it possible to distinguish many features in the painting, such as bone black remains of the original hat (P, Ca maps), and the now discolored smalt-rich background (Co, Ni, As, K maps). The arsenic (As) map also revealed areas of high-intensity in Isaac's sleeve and Rebecca's dress where it could be established that it was not related with the pigment smalt that also contains arsenic. This pointed to the presence of a yellow or orange arsenic-containing pigment, such as realgar or orpiment that is not associated with the artist's palette. Subsequent examination of existing paint cross-sections from these locations taken by Karin Groen in the 1990s identified isolated, almost perfectly round particles of arsenic sulfide. The round shape corresponds with published findings on a purified form of artificial orpiment glass obtained by dry processing, a sublimation reaction. In bright field, the particles characteristically exhibit a dark cross in the middle caused by internal light reflections. The results of additional non-invasive techniques (portable XRD and portable Raman) are discussed, as well as the implications of this finding and how it fits with Rembrandt's late experimental painting technique.
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Publisher Place of Publication Editor
Language Wos 000404916400001 Publication Date 2017-06-02
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2050-7445 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited 6 Open Access
Notes ; This research is part of the Science4Arts Program, funded by the Netherlands Organization for Scientific Research (NWO) (Grant No. SFA-11-12). GVdS is supported by the Baillet Latour Fund. The authors would like to thank Lisette Vos, Rijksmuseum Amsterdam, for assisting with the MA-XRF scanning; Arisa Izumi and Airi Hirayama, students of the Tokyo University of Science, and Frederik Vanmeert, University of Antwerp, for assisting with the pXRD and pRaman measurements. We are also grateful to Rob Erdmann, Rijksmuseum Amsterdam, who made the curtain viewer to facilitate comparison of the visible image with the elemental distribution maps of the painting. ; Approved Most recent IF: NA
Call Number UA @ admin @ c:irua:144864 Serial 5479
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