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Author Vincze, L.; Vekemans, B.; Adams, F.
Title Synchrotron computed X-ray fluorescence microtomography in environmental and earth sciences Type P3 Proceeding
Year 2003 Publication Abbreviated Journal
Volume Issue Pages
Keywords P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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Notes Approved no
Call Number UA @ admin @ c:irua:43187 Serial 8632
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Author Vincze, L.; Vekemans, B.; Adams, F.
Title Synchrotron computed X-ray fluorescence tomography in environmental and earth sciences: radiation Type P3 Proceeding
Year 2004 Publication Abbreviated Journal
Volume Issue Pages
Keywords P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
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ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:46497 Serial 8633
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Author Adams, F.; Vincze, L.; Vekemans, B.
Title Synchrotron radiation for microscopic X-ray fluorescence analysis Type H3 Book chapter
Year 2004 Publication Abbreviated Journal
Volume Issue Pages 343-353 T2 - X-ray spectrometry: recent technologi
Keywords H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
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ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:46499 Serial 8634
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Author Smits, J.; Van Grieken, R.
Title Synthesis of a chelating cellulose filter with 2,2-diaminodiethylamine functional groups Type A3 Journal article
Year 1978 Publication Zeitschrift für angewandte Makromolekare Chemie Abbreviated Journal
Volume 72 Issue Pages 105-113
Keywords A3 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
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ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116644 Serial 8637
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Author Van Loenhout, J.
Title Targeting pancreatic ductal adenocarcinoma and glioblastoma with oxidative stress-mediated treatment strategies : focus on tumor cell death and modulation of the tumor microenvironment Type Doctoral thesis
Year 2021 Publication Abbreviated Journal
Volume Issue Pages 167 p.
Keywords Doctoral thesis; Plasma Lab for Applications in Sustainability and Medicine – Antwerp (PLASMANT); Center for Oncological Research (CORE)
Abstract Pancreatic ductal adenocarcinoma (PDAC) and glioblastoma multiforme (GBM) are two of the most malignant solid tumor types with poor survival rates, which underscore the urgency of novel and efficacious treatment strategies. Within the last decade, immunotherapy has been established as a breakthrough in cancer therapy. This mainly has been driven by the clinical data and approval associated with several immune checkpoint inhibitors (e.g. anti-CTLA-4 and anti-PD-1/L1). Despite the clinical benefit in specific tumor types, these inhibitors have not yet fulfilled their promise in low immunogenic tumors such as PDAC and GBM. Oxidative stress in cancer cells due to elevated reactive oxygen species (ROS) and an inability to balance intracellular redox state has recently been highlighted as promising target for anticancer treatment strategies with possible immunogenic effects. In this PhD dissertation, I investigated novel oxidative stress-mediated treatment approaches to target PDAC and GBM and to enhance immunogenicity by inducing immunogenic cell death (ICD). In the first part of this thesis (chapter 2), I reviewed the mechanistic responses of cancer cells towards different oxidative stress-inducing treatment strategies and their immunomodulating effects. The resulting literature demonstrated that different exogenous and endogenous ROS-inducing therapies show direct and indirect immunomodulating effects, which can be either immunostimulatory or immunosuppressive. One of the indirect immunostimulatory effects of the ROS-mediating therapies is the capacity of inducing immunogenic cell death (ICD) in tumor cells, which can increase the immunogenicity and consequently can trigger an antitumoral immune response. In chapter 3, I investigated a novel exogenous ROS-inducing treatment method, namely cold atmospheric plasma, to determine the therapeutic and ICD-inducing effects in PDAC, in vitro. I revealed that plasma-treated PBS (pPBS) has the potential to induce ICD in pancreatic cancer cells (PCCs) and to reduce the immunosuppressive tumor microenvironment (TME) by attacking the tumor supportive pancreatic stellate cells (PSCs). Although the cell death induced in PSCs was non-immunogenic as seen by the lack of danger-associated molecular patterns (DAMPs) emission and DC activation, I showed that pPBS could disrupt the physical barrier and lower the immunosuppressive secretion profile (lower TGF-β) of PSCs. In contrast, DAMPs were released by PCCs after treatment with pPBS which resulted in activation and maturation of DCs and a more immunostimulatory secretion profile (higher TNF-α, IFN-γ). Hence, indirect plasma treatment via pPBS has the potential to enhance immunogenicity in PDAC by triggering ICD and by attacking the immunosuppressive PSCs. Tumor cells can evolve adaptation mechanisms to protect themselves against intrinsic oxidative stress by upregulation of pro-survival molecules and their antioxidant defense system to maintain the redox balance. As such, tumor cells can become resistant towards exogenous ROS-inducing therapies, like plasma. Dual targeting of the redox balance of tumor cells by increasing exogenous levels of ROS and inhibiting the antioxidant defense system can maximally exploit ROS-mediated cell death mechanisms as therapeutic anticancer strategy. In this regard, cold atmospheric plasma was combined with auranofin, a thioredoxin reductase inhibitor, in GBM (chapter 4). A synergistic effect was shown after this combination treatment in 2D and 3D, however, in 3D only high concentrations of auranofin synergized with plasma treatment. I confirmed a ROS-mediated response after combination treatment, which was able to induce distinct cell death mechanisms, specifically apoptosis and ferroptosis. Additionally, the auranofin and plasma combined treatment strategy induced cell death, which resulted in an increased release of DAMPs. Together with the observed DC maturation, these results indicates the potential increase in immunogenicity, though, the phagocytotic capacity of DCs was inhibited by auranofin. In chapter 5, I evaluated this promising oxidative stress combination therapy in GBM, in vivo. A decrease in tumor kinetics and an increased survival in GBM-bearing mice was observed when auranofin was sequentially combined with direct plasma treatment. No T cell infiltration was observed after auranofin monotherapy. However, further characterization of the TME after the combination therapy is necessary to provide more insight in the immunogenic effects in vivo. In conclusion, this PhD dissertation comprises novel and important therapeutic and immunogenic insights in cold atmospheric plasma and auranofin as promising oxidative stress-mediated treatment strategies for low immunogenic tumors, like PDAC and GBM. These preclinical results provide a solid basis for future research towards combinations with immunotherapeutic approaches.
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Impact Factor Times cited Open Access
Notes Approved Most recent IF: NA
Call Number UA @ admin @ c:irua:181309 Serial 8643
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Author Gielis, J.
Title Temperate bamboos in ornamental horticulture: differentiators and spillover effects into the 21st century Type H3 Book chapter
Year 2012 Publication Abbreviated Journal
Volume Issue Pages 603-623 T2 - Proceedings of the 9th World Bamboo C
Keywords H3 Book chapter; Engineering sciences. Technology; Sustainable Energy, Air and Water Technology (DuEL)
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Notes Approved no
Call Number UA @ admin @ c:irua:97755 Serial 8644
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Author Potgieter-Vermaak, S.; Stranger, M.; Verlinden, L.; Roekens, E.; Van Grieken, R.
Title NO2 verkeersmetingen in Vlaanderen door passieve bemonstering Type A1 Journal article
Year 2008 Publication Die Suid-Afrikaanse tydskrif vir natuurwetenskap en tegnologie Abbreviated Journal
Volume 27 Issue 4 Pages 266-286
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
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Series Editor Series Title Abbreviated Series Title
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ISSN 0254-3486; 2222-4173 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:72494 Serial 8650
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Author Koldeweij, J.; Hoogstede, L.; Ilsink, M.; Janssens, K.; De Keyser, N.; Gotink, R.K.; Legrand, S.; Nauhaus, J.M.; van der Snickt, G.; Spronk, R.
Title The patron of Hieronymus Bosch's 'Last Judgment' triptych in Vienna Type A1 Journal article
Year 2018 Publication The Burlington magazine Abbreviated Journal
Volume 160 Issue 1379 Pages 106-111
Keywords A1 Journal article; Art; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract A technical examination of the Last Judgment triptych by Hieronymus Bosch in the Paintings Gallery of the Academy of Fine Arts, Vienna, has revealed a painted escutcheon with the coat of arms of the Burgundian court official Hippolyte de Berthoz underneath the current surface of the right outer wing. This allows him to be firmly identified as the painting's patron.
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Publisher Place of Publication Editor
Language Wos 000458246800007 Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0007-6287; 2044-9925 ISBN Additional Links UA library record; WoS full record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:181267 Serial 8656
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Author Xiao, Y.
Title Theoretical study of the optoelectronic properties of new type 2DEG materials : multilayer graphene and monolayer MoS2 Type Doctoral thesis
Year 2017 Publication Abbreviated Journal
Volume Issue Pages 144 p.
Keywords Doctoral thesis; Condensed Matter Theory (CMT)
Abstract
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Notes Approved no
Call Number UA @ admin @ c:irua:144948 Serial 8661
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Author Taghizadeh Sisakht, E.
Title Tight-binding investigation of the electronic properties of phosphorene and phosphorene nanoribbons Type Doctoral thesis
Year 2019 Publication Abbreviated Journal
Volume Issue Pages 150 p.
Keywords Doctoral thesis; Condensed Matter Theory (CMT)
Abstract abstract not available
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Notes Approved no
Call Number UA @ admin @ c:irua:166195 Serial 8670
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Author Nakhaee, M.
Title Tight-binding model for two-dimensional materials Type Doctoral thesis
Year 2020 Publication Abbreviated Journal
Volume Issue Pages 139 p.
Keywords Doctoral thesis; Condensed Matter Theory (CMT)
Abstract abstract not available
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Series Editor Series Title Abbreviated Series Title
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Impact Factor Times cited Open Access
Notes Approved Most recent IF: NA
Call Number UA @ admin @ c:irua:166134 Serial 8671
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Author Yu, H.; Schaekers, M.; Chew, S.A.; Eyeraert, J.-L.; Dabral, A.; Pourtois, G.; Horiguchi, N.; Mocuta, D.; Collaert, N.; De Meyer, K.
Title Titanium (germano-)silicides featuring 10-9 Ω.cm2 contact resistivity and improved compatibility to advanced CMOS technology Type P1 Proceeding
Year 2018 Publication 2018 18th International Workshop On Junction Technology (iwjt) Abbreviated Journal
Volume Issue Pages 80-84 T2 - 18th International Workshop on Junction
Keywords P1 Proceeding; Plasma Lab for Applications in Sustainability and Medicine – Antwerp (PLASMANT)
Abstract uIn this work, we discuss three novel Ti (germano-)silicidation techniques featuring respectively the pre-contact amorphization implantation (PCAI), the TiSi co-deposition, and Ti atomic layer deposition (ALD). All three techniques form TiSix(Ge-y) contacts with ultralow contact resistivity (rho(c)) of (1-3)x10(-9) Omega.cm(2) on both highly doped n-Si and p-SiGe substrates: these techniques meet rho(c) requirement of 5-14 nm CMOS technology and feature unified CMOS contact solutions. We further discuss the compatibility of these techniques to the realistic CMOS transistor fabrication.
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Publisher Place of Publication Editor
Language Wos 000502768600020 Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 978-1-5386-4511-6; 978-1-5386-4511-6 ISBN Additional Links UA library record; WoS full record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:165190 Serial 8673
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Author De Clippeleir, H.; Vlaeminck, S.E.; Courtens, E.N.P.; Jimenez, J.; Wadhawan, T.; Zhang, Q.
Title Toward energy autarky : carbon redirection coupled with shortcut nitrogen processes Type H3 Book chapter
Year 2015 Publication Abbreviated Journal
Volume Issue Pages 129-150 T2 - Shortcut nitrogen removal : nitrite s
Keywords H3 Book chapter; Engineering sciences. Technology; Sustainable Energy, Air and Water Technology (DuEL)
Abstract
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Series Editor Series Title Abbreviated Series Title
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ISSN ISBN 978-1-57278-313-3 Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:130470 Serial 8676
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Author Gielis, J.; Ding, Y.; Shi, P.
Title Towards a geometrical theory of morphology and morphogenesis Type P3 Proceeding
Year 2016 Publication Abbreviated Journal
Volume Issue Pages
Keywords P3 Proceeding; Engineering sciences. Technology; Sustainable Energy, Air and Water Technology (DuEL)
Abstract
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Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:144548 Serial 8677
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Author Mozo, I.; Lacoste, L.; aussenac, J.; De Cocker, P.; Vlaeminck, S.E.; Sperandio, M.; Caligaris, M.; Graveleau, L.; Barillon, B.; Martin Ruel, S.
Title Towards application of mainstream deammonification on municipal wastewater in warm and cold areas Type P3 Proceeding
Year 2016 Publication Abbreviated Journal
Volume Issue Pages 4 p. T2 - World Cities Summit, Singapore Internati
Keywords P3 Proceeding; Engineering sciences. Technology; Sustainable Energy, Air and Water Technology (DuEL)
Abstract
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Notes Approved no
Call Number UA @ admin @ c:irua:151124 Serial 8678
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Author Mozo, I.; Lacoste, L.; Aussenac, J.; De Cocker, P.; Vlaeminck, S.E.; Sperandio, M.; Caligaris, M.; Barillon, B.; Martin Ruel, S.
Title Towards application of mainstream deammonification on municipal wastewater in warm and cold areas Type P3 Proceeding
Year 2016 Publication Abbreviated Journal
Volume Issue Pages 4 p. T2 - WEF/IWA Nutrient Removal and Recovery Co
Keywords P3 Proceeding; Engineering sciences. Technology; Sustainable Energy, Air and Water Technology (DuEL)
Abstract
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Notes Approved no
Call Number UA @ admin @ c:irua:151136 Serial 8679
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Author Alloul, A.; Vlaeminck, S.E.
Title Towards upgrading of wastewater resources to microbial protein : volatile fatty acids impacting growth kinetics and yield of purple bacteria Type P3 Proceeding
Year 2017 Publication Abbreviated Journal
Volume Issue Pages 2 p. T2 - 5th IWA Benelux Young Water Professional
Keywords P3 Proceeding; Engineering sciences. Technology; Sustainable Energy, Air and Water Technology (DuEL)
Abstract
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Notes Approved no
Call Number UA @ admin @ c:irua:151115 Serial 8683
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Author Van Grieken, R.E.; LaBrecque, J.J.
Title Trace analysis of environmental samples by X-ray emission spectroscopy Type H3 Book chapter
Year 1985 Publication Abbreviated Journal
Volume Issue Pages 101-183 T2 - Trace analysis : vol. 4 / Lawrence, J
Keywords H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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Notes Approved no
Call Number UA @ admin @ c:irua:117495 Serial 8686
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Author Artaxo, P.; Rabello, M.L.C.; Maenhaut, W.; Van Grieken, R.
Title Trace elements and individual particle analysis of atmospheric aerosols from the Antarctic peninsula Type A3 Journal article
Year 1992 Publication Tellus Abbreviated Journal
Volume 44b Issue Pages 318-334
Keywords A3 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:2845 Serial 8689
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Author Costa Dantas, C.; Moura de Amorim, W.; Van 't dack, L.; Van Grieken, R.
Title Trace elements in the atmospheric aerosols and soils in and around Recife, N.E. Brasil Type A3 Journal article
Year 1980 Publication Ciencia e cultura Abbreviated Journal
Volume 32 Issue Pages 1525-1532
Keywords A3 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0009-6725 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:111434 Serial 8690
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Author Van Grieken, R.E.; Johansson, T.B.; Winchester, J.W.
Title Trace metal fractionation effects between sea water and aerosols from bubble bursting Type A1 Journal article
Year 1974 Publication Journal de recherches atmosphériques Abbreviated Journal
Volume 8 Issue 3-4 Pages 611-621
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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Series Editor Series Title Abbreviated Series Title
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ISSN 0021-7972 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:113641 Serial 8693
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Author Winchester, J.W.; Meinert, D.L.; Nelson, J.W.; Johansson, T.B.; Van Grieken, R.E.; Orsini, C.; Kaufmann, H.C.; Akselsson, R.
Title Trace metals in the St-Louis aerosol Type H3 Book chapter
Year 1975 Publication Abbreviated Journal
Volume Issue Pages 385-394 T2 - Nuclear techniques in environmental r
Keywords H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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Notes Approved no
Call Number UA @ admin @ c:irua:117459 Serial 8694
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Author Vandekerckhove, T.; Courtens, E.N.P.; Prat, D.; Vilchez-Vargas, R.; Vital, M.; Pieper, D.H.; Meerbergen, K.; Lievens, B.; Boon, N.; Vlaeminck, S.E.
Title Transitioning from mesophilic to thermophilic nitrification: shaping a niche for archaeal ammonia oxidizers Type P3 Proceeding
Year 2016 Publication Abbreviated Journal
Volume Issue Pages 9 p. T2 - WEF/IWA Nutrient Removal and Recovery Co
Keywords P3 Proceeding; Engineering sciences. Technology; Sustainable Energy, Air and Water Technology (DuEL)
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Notes Approved no
Call Number UA @ admin @ c:irua:151126 Serial 8697
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Author Subramanian, V.; Van Grieken, R.; Van 't dack, L.
Title Transport and fractionation of Pb in river sediments from the Indian sub-continent Type A1 Journal article
Year 1987 Publication Journal of the Geological Society of India Abbreviated Journal
Volume 30 Issue Pages 217-226
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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Series Editor Series Title Abbreviated Series Title
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ISSN 0016-7622 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:111506 Serial 8699
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Author Hoornaert, S.; Treiger, B.; Van Grieken, R.; Laane, R.
Title Trend analysis of the published concentrations of heavy metals in aerosols above the North Sea and the English Channel for the period 1971-1994 Type A1 Journal article
Year 1999 Publication Environmental reviews Abbreviated Journal
Volume 7 Issue Pages 191-202
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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Series Editor Series Title Abbreviated Series Title
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ISSN 1181-8700 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:27590 Serial 8700
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Author Verbueken, A.H.; van de Vijver, F.L.; Van Grieken, R.E.; Paulus, G.J.; Visser, W.J.; d'Haese, P.; de Broe, M.E.
Title Ultrastructural localization of aluminum in patients with dialysis-associated osteomalacia Type A1 Journal article
Year 1984 Publication Clinical chemistry : international journal of laboratory medicine and molecular diagnostics Abbreviated Journal
Volume 30 Issue 5 Pages 763-768
Keywords A1 Journal article; Pharmacology. Therapy; Pathophysiology; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Laboratory Experimental Medicine and Pediatrics (LEMP)
Abstract Using laser microprobe mass analysis, we studied the ultrastructural localization of aluminum in liver and bone tissue of chronic-hemodialysis patients with proven aluminum-induced osteomalacia. In the liver, aluminum was observed to be almost exclusively associated with iron. Detectable aluminum and large amounts of iron were found in lysosomes of both hepatocytes and Kupffer cells. In bone, aluminum was localized at the osteoid/calcified-bone interface and also was associated with iron in some cases.
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Publisher Place of Publication Editor
Language Wos A1984SR66500043 Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0009-9147; 1530-8561 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116713 Serial 8703
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Author Worobiec, A.; de Hoog, J.; Osán, J.; Szalóki, I.; Joos, P.; Van Grieken, R.
Title Unconventional microanalysis for low-Z, volatile and organic aerosol compounds Type A1 Journal article
Year 2000 Publication Journal of aerosol science Abbreviated Journal
Volume 31 Issue S1 Pages 384-385
Keywords A1 Journal article; Laboratory Experimental Medicine and Pediatrics (LEMP); AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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ISSN 0021-8502; 1879-1964 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:31639 Serial 8704
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Author Mishra, V.K.; Dons, E.; Panis, L.I.; Frijns, E.; van Poppel, M.; Berghmans, P.; Bleux, N.; Wuyts, K.; Samson, R.
Title Understanding ultrafine particles dynamics within a one km urban grid Type P3 Proceeding
Year 2010 Publication Abbreviated Journal
Volume Issue Pages
Keywords P3 Proceeding; Sustainable Energy, Air and Water Technology (DuEL)
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Notes Approved no
Call Number UA @ admin @ c:irua:88671 Serial 8709
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Author de Gendt, S.; Kenis, K.; Mertens, P.W.; Heyns, M.M.; Claes, M.; Van Grieken, R.E.; Bailleul, A.; Knotter, M.; de Bokx, P.K.
Title Use of grazing emission XRF spectrometry for silicon wafer surface contamination measurements Type P3 Proceeding
Year 1996 Publication Abbreviated Journal
Volume Issue Pages
Keywords P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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Notes Approved no
Call Number UA @ admin @ c:irua:14679 Serial 8720
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Author Torfs, K.M.; Van Grieken, R.E.; Buzek, F.
Title Use of stable isotope measurements to evaluate the origin of suphur in gypsum layers on limestone buildings Type A1 Journal article
Year 1997 Publication Environmental science and technology Abbreviated Journal
Volume 31 Issue Pages 2650-2655
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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Series Editor Series Title Abbreviated Series Title
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ISSN 0013-936x; 1520-5851 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:18784 Serial 8724
Permanent link to this record