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Author Markowicz, A.A.; Van Grieken, R.E.
Title Quantification in XRF analysis of intermediate-thickness samples Type H3 Book chapter
Year 2002 Publication Abbreviated Journal
Volume Issue Pages 407-431 T2 - Handbook of X-ray spectrometry / Grie
Keywords H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:36389 Serial 8433
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Author Markowicz, A.M.; Van Grieken, R.E.
Title Quantification in XRF analysis of intermediate-thickness samples Type H3 Book chapter
Year 1992 Publication Abbreviated Journal
Volume Issue Pages 339-358 T2 - Handbook of X-ray spectroscopy / Grie
Keywords H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:2855 Serial 8434
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Author Schelles, W.; Van Grieken, R.
Title Quantitative analysis of zirconium oxide by direct glow discharge mass spectrometry using a secondary cathode Type A1 Journal article
Year 1997 Publication Journal of analytical atomic spectrometry Abbreviated Journal
Volume 12 Issue Pages 49-52
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0267-9477 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:18774 Serial 8439
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Author Piñera, I.; Abreu, Y.; van Espen, P.; Diaz, A.; Leyva, A.; Cruz, C.M.
Title Radiation damage evaluation on LYSO and LuYAP materials through Dpa calculation assisted by Monte Carlo method Type P1 Proceeding
Year 2011 Publication IEEE conference record T2 – IEEE Nuclear Science Symposium/Medical Imaging Conference (NSS/MIC)/18th, International Workshop on Room-Temperature Semiconductor X-Ray and, Gamma-Ray Detectors, OCT 23-29, 2011, Valencia, SPAIN Abbreviated Journal
Volume Issue Pages 1609-1611
Keywords P1 Proceeding; Engineering sciences. Technology; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract The aim of the present work is to study the radiation damage induced in LYSO and LuYAP crystals by the gamma radiation and the secondary electrons/positrons generated. The displacements per atom (dpa) distributions inside each material were calculated following the Monte Carlo assisted Classical Method (MCCM) introduced by the authors. As gamma sources were used Sc-44, Na-22 and V-48. Also the energy of gammas from the annihilation processes (511 keV) was included in the study. This procedure allowed studying the in-depth dpa distributions inside each crystal for all four sources. It was also possible to obtain the separate contribution from each atom to the total dpa. The LYSO crystals were found to receive more damage, mainly provoked by the displacements of silicon and oxygen atoms.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000304755601169 Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 978-1-4673-0120-6 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:113072 Serial 8447
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Author Chakravorty, R.; Van Grieken, R.
Title Radiochemical study of Cd, Co and Eu-coprecititation with iron hydroxide in seawater Type A3 Journal article
Year 1986 Publication Mikrochimica acta Abbreviated Journal
Volume 3 Issue Pages 81-87
Keywords A3 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0344-838x ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116774 Serial 8450
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Author Otten, P.; Bruynseels, F.; Van Grieken, R.
Title Reaction of marine aerosols with HNO3 vapour studied by single particle analysis Type P3 Proceeding
Year 1986 Publication Abbreviated Journal
Volume Issue Pages
Keywords P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:117508 Serial 8455
Permanent link to this record
 

 
Author Claes, M.; de Bokx, P.; Van Grieken, R.
Title Recent developments of laboratory grazing emission X-ray fluorescence spectrometry Type P1 Proceeding
Year 1999 Publication Abbreviated Journal
Volume Issue Pages 103-107 T2 - Proceedings of the European Conferenc
Keywords P1 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000081658400015 Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record; WoS full record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:24718 Serial 8459
Permanent link to this record
 

 
Author Bruynseels, F.; Van Grieken, R.
Title Recombination reactions and geometry effects in laser microprobe mass analysis studied with 12C/13C bilayers Type P3 Proceeding
Year 1986 Publication Abbreviated Journal
Volume Issue Pages
Keywords P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:117512 Serial 8462
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Author Injuk, J.; Van Grieken, R.
Title Reference matarials for microanalytical nuclear techniques Type P3 Proceeding
Year 1995 Publication Abbreviated Journal
Volume Issue Pages
Keywords P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:55574 Serial 8467
Permanent link to this record
 

 
Author Kabsch-Korbutowicz, M.; Krupinska, B.
Title Removal of natural organic matter from water by using ion-exchange resins Type A1 Journal article
Year 2008 Publication Przemysl chemiczny T2 – Scientific and Technical Conference on Water and Wastewater Basis for, Environmental Protection (School of Quality Water 2008), MAY 28-30, 2008, Kolobrzeg, POLAND Abbreviated Journal
Volume 87 Issue 5 Pages 473-475
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract Four aq. solns. contg. natural peat components and the water from Odra river were treated with 3 anion-exchange resins (2.5 to 15 cm(3) of resin per 1 dm(3) of the sample) for 5-60 min to remove the org. matter. The process efficiency was detd. by UV absorbance (254 nm) and colour intensity measurements. The treatment resulted in discoloration of the solns. A resin with weak alky, was the most efficient. The degree of removal increased with increasing the resin dose and contact time. The presence of inorg. anions in the soins. contributed to a decrease of process effectivity.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000257179000020 Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0033-2496 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:102617 Serial 8471
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Author Tytgat, T.
Title Research and development of self-supporting TiO2 foams for removal of VOCs from ambient air Type Doctoral thesis
Year 2012 Publication Abbreviated Journal
Volume Issue Pages 164 p.
Keywords Doctoral thesis; Engineering sciences. Technology; Sustainable Energy, Air and Water Technology (DuEL)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN 978-90-5728-395-6 Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:104607 Serial 8472
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Author Kontozova, V.; Krupińska, B.; Van Grieken, R.; Janssen, E.; Moris, H.; Aerts, D.; Watteeuw, L.; van Bos, M.; Peckstadt, A.
Title Research for preventive conservation and optimal presentation of world heritage in Museum Plantin-Moretus, Antwerp Type P3 Proceeding
Year 2011 Publication Abbreviated Journal
Volume Issue Pages
Keywords P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN 978-989-97522-0-7 Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:92095 Serial 8473
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Author Swerling, G.; Travaglini, B.; Van Grieken, R.; Spolnik, Z.; Bencs, L.; [et al.]; European Project Freindly-Heating
Title Il riscaldamento nelle chiese e la conservazione dei beni culturali = Church heating and the preservation of the cultural heritage Type ME2 Book as editor or co-editor
Year 2006 Publication Abbreviated Journal
Volume Issue Pages 240 p.
Keywords ME2 Book as editor or co-editor; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN 88-370-5034-8 Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:61684 Serial 8480
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Author Vandekerckhove, T.G.L.; Courtens, E.N.P.; Prat, D.; Boon, N.; Vlaeminck, S.E.
Title The rise of thermophilic biotechnology for nitrogen removal Type P3 Proceeding
Year 2016 Publication Abbreviated Journal
Volume Issue Pages 17 p. T2 - WEF/IWA Nutrient Removal and Recovery C
Keywords P3 Proceeding; Engineering sciences. Technology; Sustainable Energy, Air and Water Technology (DuEL)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up)
Series Editor Series Title Abbreviated Series Title
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ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:151125 Serial 8481
Permanent link to this record
 

 
Author Potgieter-Vermaak, S.; Van Grieken, R.; Potgieter, H.
Title Die risikoprofiel van Pb en Cr in stedelike padstof Type A2 Journal article
Year 2012 Publication Litnet akademies : 'n joernaal vir die geesteswetenskappe Abbreviated Journal
Volume 9 Issue 3 Pages 1-22
Keywords A2 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract The risk profile of Cr and Pb in urban road deposited sediment Exponential urbanisation and industrial growth occur on a global scale and result in an ecological burden, of which one important part is pollution. It is well known that the extent of air pollution has escalated over the past two decades in several parts of the world, despite mitigating measures and legislation. Current research points to the fact that air pollution in urban and industrial areas is substantially different from that found in rural areas. Road dust (RD) contributes up to 35% of airborne particulate matter due to resuspension thereof, and poses a health concern due to carcinogenic and toxic components potentially present in the micron-sized fractions. Although literature does report on the concentrations of trace, toxic metals and metalloids present in RD (Hooker and Nathanail 2006), the molecular make-up of particulates generated due to the resuspension of the RD is not well documented. In vitro and animal toxicological studies have confirmed that the chemical composition of inhaled particles plays a major role in its toxic, genotoxic and carcinogenic mechanisms, but the component-specific toxic effects are still not understood. Transition metals binding to air particle matter can result in reactive oxygen species in the human body (particularly in the lungs), and this is a significant risk, especially for vulnerable population groups like elderly people, children and terminally ill patients. The characterisation of the molecular composition of the fine fraction is evidently of importance for public health. During an earlier study, road dust from an inner-city environment in the UK was collected and partially characterised (Barrett e.a. 2010). These same-size fractions were analysed for their elemental concentrations, using X-ray Fluorescence Spectrometry (XRFS) and Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In addition, single-particle analysis was performed on the different fractions by means of Computer Controlled Electron Probe X-ray Micro Analysis (CC-EPXMA) and their molecular structure probed by studying elemental associations. These findings were correlated with Micro Raman Spectroscopy (MRS) results. It was found that the fine fraction (<38 μm) had the highest Pb (238 ppm) and Cr (171 ppm) concentrations. The CC-EPXMA data showed >50% association of Cr-rich particles with Pb and the MRS data showed that the Cr was mostly present as lead chromate and therefore in the Cr(VI) oxidation state. Concentrations of both Pb and Cr decreased substantially (279 (<38 mm) 13 ppm (<1mm); 171 (<38 mm) 91 ppm (<1mm) respectively) in the larger fractions. Apart from rather alarmingly high concentrations of oxidative stressors (Cu, Fe, Mn), the carcinogenic and toxic potential of the inhalable fraction is evident. Preliminary bioaccessibility data indicated that both Cr and Pb are readily
Address
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Series Editor Series Title Abbreviated Series Title
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ISSN 1995-5928 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:102566 Serial 8482
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Author Moropoulou, A.; Bisbikou, K.; Torfs, K.; Van Grieken, R.
Title Risk analysis for the protection of cultural heritage from industrial pollution Type H3 Book chapter
Year 1999 Publication Abbreviated Journal
Volume Issue Pages 475-484 T2 - Structural studies, repairs and maint
Keywords H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:27598 Serial 8483
Permanent link to this record
 

 
Author Chou, L.; Harlay, J.; Roevros, N.; Lannuzel, D.; Rebreanu, L.; van der Zee, C.; Lapernat, P.-E.; Daro, M.-H.; Aerts, K.; Godoi, R.; Van Grieken, R.
Title Role of oceanic production and dissolution of calcium carbonate in climate change (CCCC): final report Type Minutes and reports
Year 2009 Publication Abbreviated Journal
Volume Issue Pages
Keywords Minutes and reports; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up)
Series Editor Series Title Abbreviated Series Title
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ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:80696 Serial 8486
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Author Delalieux, F.; Van Grieken, R.; Moropoulou, A.
Title Salt weathering research: present state and future directions Type P3 Proceeding
Year 2003 Publication Abbreviated Journal
Volume Issue Pages
Keywords P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up)
Series Editor Series Title Abbreviated Series Title
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ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:42732 Serial 8490
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Author van der Snickt, G.; de Boeck, A.; Keutgens, K.; Anthierens, D.
Title The SALUT project : study of advanced laser techniques for the uncovering of polychromed works of art Type P1 Proceeding
Year 2007 Publication Abbreviated Journal
Volume 116 Issue Pages 151-158 T2 - Proceedings of the 6th International
Keywords P1 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract In order to find out whether the existing laser systems can be employed to remove superimposed layers of paint on secco wall paintings in a selective way, laser tests were carried out on three types of prepared samples simulating three stratigraphies that are frequently encountered in practice. OM, EPMA, colorimetry, mu Raman, and FT-IR were used to evaluate the results. It was found that Q-switched Nd:YAG lasers emitting at 1,064 nm could be employed to remove unwanted layers of oil paint and limewash, but the treatment of large areas requires implementation of a computer-controlled X-Y-Z station in order to control the parameters. However, the applicability of this technique will remain limited as ablation at the established optimum parameters implied a discoloration of the pigments cinnabar, yellow ochre, and burnt sienna. Moreover, it was observed that no ablation took place when the limewash thickness exceeds 25 mu m. Unwanted layers of acrylic could be removed in an efficient way with an excimer laser emitting at 193 nm.
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Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000252680500018 Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 978-3-540-72129-1; 0930-8989 ISBN Additional Links UA library record; WoS full record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:157216 Serial 8491
Permanent link to this record
 

 
Author Schmeling, M.; Van Grieken, R.E.
Title Sample preparation for X-ray fluorescence Type H3 Book chapter
Year 2002 Publication Abbreviated Journal
Volume Issue Pages 933-976 T2 - Handbook of X-ray spectrometry / Grie
Keywords H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:36388 Serial 8494
Permanent link to this record
 

 
Author Injuk, J.; Van Grieken, R.
Title Sample preparation for X-ray fluorescence analysis Type H3 Book chapter
Year 2000 Publication Abbreviated Journal
Volume 15 Issue Pages 13338-13347 T2 - Encyclopedia of analytical chemis
Keywords H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:31656 Serial 8495
Permanent link to this record
 

 
Author Injuk, J.; Van Grieken, R.E.
Title Sample preparation for XRF Type H3 Book chapter
Year 1992 Publication Abbreviated Journal
Volume Issue Pages 657-692 T2 - Handbook of X-ray spectroscopy / Grie
Keywords H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
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Corporate Author Thesis
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Language Wos Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:2857 Serial 8496
Permanent link to this record
 

 
Author Robberecht, H.; Van Grieken, R.
Title Selenium content and speciation in environmental waters determied by X-ray fluorescence spectroscopy Type H3 Book chapter
Year 1980 Publication Abbreviated Journal
Volume Issue Pages 362-366 T2 - Trace substances in environmental hea
Keywords H3 Book chapter; Pharmacology. Therapy; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
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Series Editor Series Title Abbreviated Series Title
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ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:117481 Serial 8505
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Author vanden Berghe, D.; Deelstra, H.; Robberecht, H.; Van Grieken, R.
Title Selenium content of soils and rye grass (Lolium multiflorum) in Belgium Type H3 Book chapter
Year 1981 Publication Abbreviated Journal
Volume Issue Pages 85-105 T2 - Mineral elements '80 : part 1
Keywords H3 Book chapter; Pharmacology. Therapy; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
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Language Wos Publication Date (up)
Series Editor Series Title Abbreviated Series Title
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ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:117483 Serial 8506
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Author Robberecht, H.; Deelstra, H.; vanden Berghe, D.; Van Grieken, R.
Title Selenium gehalten van levensmiddelen geconsumeerd in België Type A3 Journal article
Year 1983 Publication Revue des fermentations et des industries alimentaires Abbreviated Journal
Volume 37 Issue Pages 188-201
Keywords A3 Journal article; Pharmacology. Therapy; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
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Publisher Place of Publication Editor
Language Wos Publication Date (up)
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0035-2071 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116701 Serial 8507
Permanent link to this record
 

 
Author Daems, E.
Title Shaping up oligonucleotides : aptamer-target recognition investigated by native mass spectrometry Type Doctoral thesis
Year 2021 Publication Abbreviated Journal
Volume Issue Pages 235 p.
Keywords Doctoral thesis; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract Aptamers are short, synthetic DNA or RNA molecules that are characterized by a specific 3D conformation which enables specific target recognition. Aptamers are promising tools in many application fields from sensing to therapeutics. One of the major challenges in the aptamer field is understanding the relationship between the sequence and what determines the higher-order structure and specific interactions with targets. Therefore, this PhD thesis focuses on the use of different mass spectrometry (MS) based approaches to characterize aptamers and their interactions. Several of these approaches are already widely applied to study other biomolecules, such as proteins, but are still largely unexplored for aptamers and oligonucleotides in general. A first focus was put on obtaining information on the higher-order structure and conformational stability of aptamers using a combination of MS and with ion mobility (IM) spectrometry by performing collision-induced unfolding (CIU) experiments. CIU was shown to hold great promise to analyze the conformational dynamics and gas-phase stabilities of aptamers. Next, the capabilities and limitations of native IM-MS for the analysis of noncovalent interactions of aptamers were demonstrated. The conformational behavior and interactions of cocaine-binding aptamers were studied and it was found that relative binding affinities of aptamers that only differ slightly in sequence and structure can be determined using native MS. Moreover, native IM-MS allowed the detection of small conformational changes upon binding of a target, which were found to be dependent on the binding mode of the aptamer. An adaptive binding mechanism was suggested for flexible aptamers that require more reorganization upon binding. In the final part of this thesis, the importance of thoroughly characterizing and validating aptamer-target interactions before using them in an application was emphasized. Moreover, the gathered insights were applied in our own development of a proof-of-concept aptamer-based sensor. This was shown by investigating the interactions of ampicillin aptamers which were found to not bind the target they were selected for in the first place. A multi-analytical approach combining complementary techniques was used for this purpose since no single technique is generally applicable to characterize all aptamers and their interactions and to obtain a comprehensive picture of the aptamer-target interactions. Furthermore, such multi-analytical approach was used to characterize a testosterone-binding aptamer while developing an aptamer-based electrochemiluminescent sensing strategy for this target. This shows the importance of native MS, in combination with other techniques, to thoroughly understand the aptamer-target interactions in the development of a designed application.
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Impact Factor Times cited Open Access
Notes Approved Most recent IF: NA
Call Number UA @ admin @ c:irua:178116 Serial 8517
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Author Koutsenogii, P.K.; van Malderen, H.; Hoornaert, S.; Van Grieken, R.; Koutsenogii, K.P.; Boufetov, N.; Makarov, V.I.; Smoljakov, B.S.; Nemirovski, A.M.; Osipova, L.P.; Krjukov, J.A.; Ivakin, E.A.; Posukh, O.L.; Bronstein, E.L.
Title Siberian Haze: complex study of aerosols in Siberia Type A3 Journal article
Year 1996 Publication Optics of the atmosphere and ocean Abbreviated Journal
Volume 9 Issue Pages 712-719
Keywords A3 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:14652 Serial 8521
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Author Zhang, Q.; De Clippeleir, H.; Al-Omari, A.; Wett, B.; Vlaeminck, S.E.; Murthy, S.
Title Sidestream deammonification on thermal hydrolysis process digestate : strategies to overcome nitritation inhibition Type P3 Proceeding
Year 2015 Publication Abbreviated Journal
Volume Issue Pages 11 p. T2 - IWA Nutrient Removal and Recovery 2015:
Keywords P3 Proceeding; Engineering sciences. Technology; Sustainable Energy, Air and Water Technology (DuEL)
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Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:151147 Serial 8522
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Author Piñera Hernández, I.
Title Simulation of atom displacements induced by photons and electrons in solids Type Doctoral thesis
Year 2014 Publication Abbreviated Journal
Volume Issue Pages 137 p.
Keywords Doctoral thesis; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116687 Serial 8526
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Author van Malderen, H.; Van Grieken, R.; Khodzher, T.V.; Grachev, M.; Bufetov, N.S.; Koutsenogii, K.P.
Title Single particle analysis of aerosols from Siberia Type P3 Proceeding
Year 1994 Publication Proceedings of the Russian-Ukrainian-Austrian-German Analytical Symposium Abbreviated Journal
Volume Issue Pages
Keywords P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
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Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:9527 Serial 8530
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