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Author Verbueken, A.H.; Van Grieken, R.E.; Paulus, G.J.; Verpooten, G.A.; de Broe, M.E.
Title Laser microprobe mass spectrometry of platinum in dog kidney after cisplatin adminstration Type A3 Journal article
Year 1984 Publication Biomedical mass spectrometry Abbreviated Journal
Volume 11 Issue 4 Pages 159-163
Keywords A3 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Laboratory Experimental Medicine and Pediatrics (LEMP)
Abstract By means of laser microprobe mass analysis (LAMMA) platinum was detected in the renal proximal tubular cells of a dog that had been intravenously adminstered the antitumor drug cisplatin (5 mg per kg body weight). No definite subcellular localization of the heavy metal was obtained. Sample prparation and analytical features are examined to increase spatial resolution of analysis while maintaining sufficient detection efficiency. The LAMMA method is destructive, but the amount and type of evaporated material can readily be determined when using LAMMA in combination with transmission electron microscopy. Instrumental optimization and standardization of mass signals is possible by using platinum-loaded, ion chelating resin beads embedded and sectioned with the tissue.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up) 2005-05-28
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0306-042x ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116712 Serial 8165
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Author Vandeputte, D.F.; Van Grieken, R.E.; Foets, B.J.J.; Misotten, L.
Title Characterization of the spheroliths present in primary atypical bandkeratopathy using laser microprobe mass analysis Type A1 Journal article
Year 1989 Publication Biomedical and environmental mass spectrometry Abbreviated Journal
Volume 18 Issue 9 Pages 753-756
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract Laser microprobe mass analysis was applied to study the chemical composition of spheroliths in the Bowman's membrane of patients suffering from primary atypical bandkeratopathy. The inclusions appear to consist mainly of calcium phosphate.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up) 2005-05-29
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0887-6134 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116824 Serial 7635
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Author Vandeputte, D.; Van Grieken, R.E.; Jacob, W.A.; Savory, J.; Bertholf, R.L.; Wills, M.R.
Title Ultrastructural localization of aluminium in liver of aluminium maltol-treated rabbits by laser microprobe mass analysis Type A1 Journal article
Year 1989 Publication Biomedical and environmental mass spectrometry Abbreviated Journal
Volume 18 Issue 8 Pages 598-602
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract By means of laser microprobe mass analysis (LAMMA), we have studied the ultrastructural localization of aluminium in livers of aluminium maltol-treated rabbits. This animal model was developed to study long-term aluminium toxicity using systemic (intravenous) administration of aluminium. We could only detect aluminium in electron-dense inclusion bodies found in large, sometimes multinucleated cells. These results prove that the actual observation of aluminium deposits in liver with LAMMA gives more information than bulk analysis and can be very useful to explore mechanisms of toxicity.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up) 2005-05-29
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0887-6134 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116817 Serial 8702
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Author Verbueken, A.H.; Bruynseels, F.J.; Van Grieken, R.E.
Title Laser microprobe mass analysis : a review of applications in the life sciences Type A3 Journal article
Year 1985 Publication Biomedical mass spectrometry Abbreviated Journal
Volume 12 Issue 9 Pages 438-463
Keywords A3 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract The characteristics and analytical utility of laser microprobe mass analysis (LAMMA) are described and evaluated, and a short history of this recent microanalytical technique is presented. A review of the areas of application of LAMMA and related laser microprobes is presented with special emphasis on applications in the life sciences.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up) 2005-05-31
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0306-042x ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116722 Serial 8153
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Author Verbueken, A.H.; Van Grieken, R.E.; Verpooten, G.A.; de Broe, M.E.; Wedeen, R.P.
Title Laser microprobe mass spectrometric identification of cyclosporine-induced intrarenal microliths in rat Type A1 Journal article
Year 1992 Publication Biological mass spectrometry Abbreviated Journal
Volume 21 Issue Pages 590-596
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Laboratory Experimental Medicine and Pediatrics (LEMP)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos A1992JU83000010 Publication Date (up) 2005-05-31
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1052-9306 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:2842 Serial 8162
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Author LaBrecque, J.J.; Beusen, J.M.; Van Grieken, R.E.
Title Analysis of lateritic material from Cerro impacto by instrumental neutron activation employing a low-energy photon semiconductor and a high-energy Ge(Li) detector Type A1 Journal article
Year 1986 Publication Applied spectroscopy Abbreviated Journal
Volume 40 Issue 2 Pages 140-144
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract Nineteen elements were determined in four different grain size fractions of a bulk geological material from Cerro Impacto for a study of the physical (mechanical) concentration process of different elements based upon the hardness of the different minerals. The analysis was performed by excitation of the sample with a high, slow neutron flux followed by gamma-ray spectroscopy with both a conventional Ge(Li) high-energy detector and a low-energy photon detector (LEPD). The accuracy of this method was studied with the use of two standard reference materials, SY-2 and SY-3, which are similar to the real samples. The values determined were also compared with a secondary target x-ray fluorescence method for all the elements that were suitable to both methods. Actually, the x-ray fluorescence method was found to be more complementary than competitive.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos A1986A085900003 Publication Date (up) 2005-07-21
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0003-7028 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116768 Serial 7448
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Author Eltayeb, M.A.H.; Van Grieken, R.E.
Title Preconcentration and XRF-determination of heavy metals in hair from Sudanese populations Type A1 Journal article
Year 1989 Publication Journal of radioanalytical and nuclear chemistry Abbreviated Journal
Volume 131 Issue 2 Pages 331-342
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract Energy-dispersive X-ray fluorescence analysis was applied for the analysis of hair. The hair samples were digested in a mixture of nitric and perchloric acid and the heavy metals were precipitated with ammonium pyrrolidine dithiocarbamate. The accuracy, precision and recovery of the method for the elements Fe, Ni, Cu, Zn and Pb were evaluated through the analysis of a standard hair sample. The procedure was applied to the analysis of hair from an occupationally exposed group of Sudanese workers and a control group. The hair of the exposed group showed a range of 80550 ppm Fe, 612 ppm Cu, 57190 ppm Zn and 703700 ppm Pb, while that of the control group had a range of 60310 ppm Fe, 722 ppm Cu, 89170 ppm Zn and 317 ppm Pb.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos A1989AL77700009 Publication Date (up) 2005-08-12
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0236-5731; 1588-2780 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116816 Serial 8399
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Author Szalóki, I.; Osán, J.; Van Grieken, R.E.
Title X-ray spectrometry Type A1 Journal article
Year 2006 Publication Analytical chemistry Abbreviated Journal
Volume 78 Issue 12 Pages 4069-4096
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos 000238252600016 Publication Date (up) 2006-06-10
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0003-2700; 5206-882x ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:58857 Serial 8771
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Author Markowicz, A.A.; Van Grieken, R.E.
Title X-ray spectrometry Type A1 Journal article
Year 1990 Publication Analytical chemistry Abbreviated Journal
Volume 62 Issue 12 Pages 101r-113r
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up) 2006-11-06
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0003-2700; 5206-882x ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116527 Serial 8779
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Author Kindratenko, V.V.; van Espen, P.J.M.; Treiger, B.A.; Van Grieken, R.E.
Title Fractal dimensional classification of aerosol particles by computer-controlled scanning electron microscopy Type A1 Journal article
Year 1994 Publication Environmental science and technology Abbreviated Journal
Volume 28 Issue Pages 2197-2202
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Chemometrics (Mitac 3)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos A1994PP82900033 Publication Date (up) 2007-05-30
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0013-936x; 1520-5851 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:9497 Serial 7983
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Author van de Vijver, F.L.; Verbueken, A.H.; Visser, W.J.; Van Grieken, R.E.; de Broe, M.E.
Title Localisation of aluminium and iron by histochemical and laster microprobe mass analytical techniques in bone marrow cells of chronic hemodialysis patients Type L1 Letter to the editor
Year 1984 Publication Journal of clinical pathology Abbreviated Journal
Volume 37 Issue 7 Pages 837-838
Keywords L1 Letter to the editor; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Laboratory Experimental Medicine and Pediatrics (LEMP)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos A1984TA05200027 Publication Date (up) 2007-06-09
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0021-9746 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116710 Serial 8178
Permanent link to this record
 

 
Author Vanderborght, B.M.; Van Grieken, R.E.
Title Trace metal analysis of water containing humic substances by X-ray fluorescence Type A1 Journal article
Year 1978 Publication International journal of environmental analytical chemistry Abbreviated Journal
Volume 5 Issue 3 Pages 221-237
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract Chelation by oxine followed by adsorption on activated carbon results in the efficient collection of many trace metal ions, independent of the trace metal concentration and of high alkali and alkaline earth ion abundances. Preconcentration factors around 10000 are often achieved. When this preconcentration procedure is combined with energy-dispersive X-ray fluorescence, accurate and precise analysis can be carried out, as was proven in several experiments. The technique can also be applied for the determination of divalent ions in natural waters containing up to 10 ppm of humic substances. Trivalent ions can quantitatively be collected from natural water provided suKicient activated carbon is added. Omitting the oxine chelation prior to the activated carbon adsorption step still results in collection of a sometimes important fraction of the trace metal ions from natural waters. This is related to organically bound or colloidal forms of the trace metals.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos A1978FR88000005 Publication Date (up) 2007-07-07
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0306-7319 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116570 Serial 8692
Permanent link to this record
 

 
Author Verbueken, A.H.; van de Vijver, F.L.; Visser, W.J.; Van Grieken, R.E.; de Broe, M.E.
Title Laser microprobe mass analysis (LAMMA) to verify the aluminon staining of bone Type A1 Journal article
Year 1986 Publication Stain technology Abbreviated Journal
Volume 61 Issue 5 Pages 287-295
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Laboratory Experimental Medicine and Pediatrics (LEMP)
Abstract Triammonium aurin tricarboxylate (aluminon) has been used to localize aluminum in 2 μm sections of undecalcified, methyl methacrylate embedded bone obtained from patients with terminal chronic renal failure. Aluminum appeared in four cases as bright red lines at the mineralized-bone boundary. In two cases, however, purplish lines were found and one patient showed red as well as purplish lines. Laser microprobe mass analysis (LAMMA) identified aluminum at the location of the red lines and both aluminum and iron at the purplish lines. Furthermore, both iron and aluminum were found in histiocytic bone marrow cells, which showed brownish aluminon staining. It appears that when aluminum and iron occur together, aluminon staining may yield aberrant results. This study shows that LAMMA can be used for the identification of elements sought by histochemical methods and thus permits the evaluation of their staining effects.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up) 2007-12-07
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0038-9153 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116764 Serial 8159
Permanent link to this record
 

 
Author Johansson, T.B.; Van Grieken, R.E.; Winchester, J.W.
Title Elemental abundance variation with particle-size in north florida aerosols Type A1 Journal article
Year 1976 Publication Journal of geophysical research Abbreviated Journal
Volume 81 Issue 6 Pages 1039-1046
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract A nonurban base line has been established for nine trace element constituents of aerosol particles as a function of particle size at ground level sampling stations in north Florida up to 50 km from the Gulf of Mexico. The particle size range 0.25- to >4-μm aerodynamic diameter was investigated by cascade impactor sampling and elemental analysis by proton-induced X ray emission. By using a strategy of sampling at urban, forest, and coastal locations and by choosing approximately 48-hour sample averaging intervals the potential dependence of the base line levels both on local pollution and natural sources and on local particle size specific aerosol removal processes could be evaluated. It is found that elements contained in the largest particles, especially those of >4 μm, display the greatest degree of average concentration difference between sites, a result suggesting short atmospheric residence times and the importance of local dispersion sources and atmospheric cleansing processes in regulating the particle concentrations in air. Elements contained in particles of <2-μm diameter show little average concentration difference between sites unless they are influenced by local pollution sources, a finding suggesting that their concentrations in air are regulated by large-scale sources and transport processes. Sulfur in the smallest particles shows a marked constancy of concentration, but it may be modified in the largest particle size ranges in relation to proximity to the seacoast. No evidence is found for dependence of particulate sulfur concentrations on local pollution sources. K, Ca, Ti, Fe, and Zn appear to be regulated in the main by terrestrial source processes, and Cl by marine source processes, but Br and Pb appear to be accounted for adequately by assuming automotive fuel combustion as their major source. Limited data obtained for V indicate that it may vary considerably with fluctuations in aerosol transport from oil-fired electric power plant sources in the region. Limited additional data also suggest that Mn is derived from sources of natural terrestrial composition. In view of these findings, certain criteria may be set for the design of a meaningful nonurban aerosol monitoring network.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos A1976BG78300001 Publication Date (up) 2008-02-06
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0148-0227; 2156-2202; 0022-1406; 0196-6928; 0196-6936; 0885-3401; 8755-8556; 0196-2256; 0747-7309; 1 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:113637 Serial 7879
Permanent link to this record
 

 
Author Vandeputte, D.F.; Ameloot, P.C.; Cleymaet, R.; Coomans, D.; Van Grieken, R.E.
Title Localization of lead and fluoride in cultured tooth germs by laser microprobe mass analysis Type A1 Journal article
Year 1990 Publication Biological trace element research Abbreviated Journal
Volume 23 Issue Pages 133-144
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract Trace elements can influence dental health, possibly by altering tooth resistance during preeruptive development. Therefore, it was investigated whether lead and fluoride would be incorporated into the calcifying matrices or the cellular parts of tooth germs in vitro. Using laser microprobe mass analysis, the localization of lead and fluoride was studied in the different layers or tooth germs that had been cultured in a medium to which PbCl2 of NaF had been added in different concentrations. Both elements could only be detected in the dentine layer. Hence, the enamel organ in the secretory stage of tooth development excludes lead and fluoride from the enamel, even when enamel formation by the ameloblasts is visibly disturbed. Furthermore, there seemed to be a process of saturation in the accumulation of lead and fluoride in the dentine.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up) 2008-06-13
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0163-4984 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116797 Serial 8182
Permanent link to this record
 

 
Author Nelson, J.W.; Williams, I.; Johansson, T.B.; Van Grieken, R.E.
Title Elemental analysis of aerosols using proton-scattering Type A1 Journal article
Year 1974 Publication IEEE transactions on nuclear science Abbreviated Journal
Volume Ns21 Issue 1 Pages 618-621
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract Elemental analysis for all of the light elements up through chlorine by elastic scattering of 16 MeV protons has been shown to be feasible. Basic problems associated with such measurements are discussed including kinematics, angular distribution, and sample backings. Spectra are presented for air particulate matter for both a total filter (Nuclepore) and a size fractionated air impactor (polystyrene backed) sample. The method is absolute, non destructive and can be used in conjunction with proton induced x-ray fluorescence to quantitatively analyze all elements in the same sample in minutes of time.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos A1974S533700086 Publication Date (up) 2008-07-22
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0018-9499 ISBN Additional Links UA library record; WoS full record; WoS citing articles
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:113642 Serial 7881
Permanent link to this record
 

 
Author Vandeputte, D.F.; Verbueken, A.H.; Jacob, W.A.; Van Grieken, R.E.
Title Laser microprobe mass analysis (LAMMA) to study lead intoxication at the subcellular level Type A3 Journal article
Year 1986 Publication Acta pharmacologica et toxicologica Abbreviated Journal
Volume 59 Issue S:7 Pages 617-619
Keywords A3 Journal article; Pharmacology. Therapy; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up) 2010-07-29
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0001-6683 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116771 Serial 8158
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Author Vandeputte, D.F.; Jacob, W.A.; Van Grieken, R.E.
Title Influence of fixation procedures on the microanalysis of lead-induced intranuclear inclusions in rat kidney Type A1 Journal article
Year 1990 Publication The journal of histochemistry and cytochemistry Abbreviated Journal
Volume 38 Issue 3 Pages 331-337
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract Using Laser Microprobe Mass Analysis (LAMMA), we studied the chemical composition of lead-induced intranuclear inclusions in rat kidney tissue prepared by three different wet chemical fixation procedures for transmission electron microscopy. Fixation with glutaraldehyde-Na2S gave the same results as fixation with glutaraldehyde only: a high lead concentration could be detected. Therefore, for lead strongly bound to proteins, precipitation procedures are not essential. Post-fixation with osmium tetroxide drastically changed the composition of the inclusions: the lead concentration decreased substantially, while sodium, calcium, and barium were introduced. The osmium tetroxide fixative was found to be the source of the contamination. It also contained aluminum, and we suggest that other proteins (e.g., in neurofibrillary tangles) might be able to take up Al out of solution and that care must be exercised in interpreting the microanalytical results of osmium-fixed material. For the microanalysis of the lead inclusions, fixation with glutaraldehyde only provides a good compromise between preservation of the ultrastructure and maintenance of the element distribution.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up) 2011-04-01
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0022-1554 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116831 Serial 8091
Permanent link to this record
 

 
Author Vandeputte, D.F.; Jacob, W.A.; Van Grieken, R.E.
Title Phosphorus, calcium and lead distribution in collagen in lead induced soft tissue calcification : an ultrastructural and X-ray microanalytical study Type A1 Journal article
Year 1990 Publication Matrix Abbreviated Journal
Volume 10 Issue 1 Pages 33-37
Keywords A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Abstract Repeated intraperitoneal injections of lead acetate in rats caused a calcification of the skin of the abdomen near the site of the injections. In the lead-induced calcifications, electron dense collagen bundles could be observed. On the surface of the collagen fibrils, needle-like crystals were visible. With energy-dispersive X-ray analysis, phosphorus, calcium and lead were detected in the electron dense collagen bundles. X-ray maps of the P-Kα, Ca-Kα, and Pb-Lα plus Pb-Lβ lines showed an equivalent distribution along the collagen fibrils for phosphorus and calcium. The occurrence of the most electron dense areas in the STEM-image was comparable to the lead distribution. A good correlation existed between the structural and the elemental images of the same area. Although the medicinal use of preparations containing lead is no longer recommended, some are still prescribed. From our results we can conclude that they should not be applied to injured or inflamed skin.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Wos Publication Date (up) 2012-04-16
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0934-8832 ISBN Additional Links UA library record
Impact Factor Times cited Open Access
Notes Approved no
Call Number UA @ admin @ c:irua:116930 Serial 8377
Permanent link to this record