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“Aptamers in biomedicine : selection strategies and recent advances”. Stefan G, Hosu O, De Wael K, Jesus Lobo-Castanon M, Cristea C, Electrochimica Acta 376, 137994 (2021). http://doi.org/10.1016/J.ELECTACTA.2021.137994
Abstract: Aptamers have come in the spotlight as bio-mimetic molecular recognition elements in the field of biomedicine due to various applications in diagnostics, drug delivery, therapeutics, and pharmaceutical analysis. Aptamers are composed of nucleic acid strands (DNA or RNA) that can specifically interact in a three-dimensional tailored design with the target molecule. The basic method to generate aptamers is Systematic Evolution of Ligands by Exponential Enrichment (SELEX). Recent technological advances in aptamer selection allow for faster and cheaper production of a new generation of high-affinity aptamers compared to the traditional SELEX, which can last up to several months. Rigorous characterization performed by multiple research groups endorsed several well-defined aptamer sequences. Binding affinity, nature of the biomolecular interactions and structural characterization are of paramount importance for aptamer screening and development of applications. However, remarkable challenges still need to be dealt with before the aptamers can make great contributions to the biomedical field. Poor specificity and sensitivity, questionable clinical use, low drug loading, in vivo stability and toxicity are only some of the identified challenges. This review accounts for the 30th celebration of the SELEX technology underlining the most important aptamers' achievements in the biomedical field within mostly the past five years. Aptamers' advantages over antibodies are discussed. Because of potential clinical translational utility, insights of remarkable developments in aptamer-based methods for diagnosis and monitoring of disease biomarkers and pharmaceuticals are discussed focusing on the recent studies (2015-2020). The current challenges and promising opportunities for aptamers for therapeutic and theragnostic purposes are also presented. (C) 2021 Elsevier Ltd. All rights reserved.
Keywords: A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
Impact Factor: 4.798
DOI: 10.1016/J.ELECTACTA.2021.137994
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“Asphalt mixture reinforced with banana fibres”. da Costa LF, de Barros AG, de Figueiredo Lopes Lucena LC, de Figueiredo Lopes Lucena AE, Road Materials And Pavement Design (2020). http://doi.org/10.1080/14680629.2020.1713866
Abstract: Stone Matrix Asphalt (SMA) is a gap-graded mixture which requires high contents of asphalt binder. To prevent draindown, natural or synthetic fibres and polymer-modified asphalt binders are conventionally used in SMA. Banana agribusiness is one of the major sources of post-harvest residue in Brazil. Amongst those residues, fibres extracted from the pseudostem of the banana plant are resistant and used in diverse purposes. The present study assesses the incorporation of fibres from the pseudostem of the banana plant in an SMA mixture. The fibre contents and lengths capable to prevent binder draindown were evaluated from draindown tests. Mechanical properties of an SMA mixture stabilised with different banana fibre lengths were analysed through the tests of Marshall stability, modified Lottman, Indirect Tensile Strength and Cantabro. The results indicated that the fibres studied are a viable alternative for SMA, stabilising draindown and improving its mechanical performance, especially at the length of 20 mm.
Keywords: A1 Journal article; Engineering sciences. Technology; Condensed Matter Theory (CMT); Energy and Materials in Infrastructure and Buildings (EMIB)
Impact Factor: 3.7
DOI: 10.1080/14680629.2020.1713866
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“Assessment of air pollutant levels in some European museums and churches”. Kontozova V, Spolnik Z, Worobiec A, Godoi R, Van Grieken R, Deutsch F, Bencs L page 245 (2005).
Keywords: H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Laboratory Experimental Medicine and Pediatrics (LEMP)
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“Assessment of air quality after the implementation of Compressed Natural Gas (CNG) as fuel in public transport in Delhi, India”. Ravindra K, Wauters E, Tyagi SK, Mor S, Van Grieken R, Environmental monitoring and assessment 115, 405 (2006). http://doi.org/10.1007/S10661-006-7051-5
Keywords: A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
DOI: 10.1007/S10661-006-7051-5
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“Assessment of atmospheric particles emitted from sugar cane burning in Southeast Brazil”. Godoi RHM, Godoi AFL, Andrade SJ, Santiago-Silva M, de Hoog J, Worobiec A, Van Grieken R, Journal od aerosol science , S749 (2003)
Keywords: A3 Journal article; Laboratory Experimental Medicine and Pediatrics (LEMP); AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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Van Grieken R, Delalieux F, Potgieter S (2003) Assessment of damage caused by air pollution. 35 p
Keywords: MA3 Book as author; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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“Assessment of homogeneity of candidate reference material at the nanogram level and investigation on representativeness of single particle analysis using electron probe X-ray microanalysis”. Ro C-U, Hoornaert S, Van Grieken R page 17 (2002).
Keywords: H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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“Assessment of homogeneity of candidate reference material at the nanogram level and investigation on representativeness of single particle analysis using electron probe X-ray microanalysis”. Ro C-U, Hoornaert S, Van Grieken R, Analytica chimica acta 389, 151 (1999). http://doi.org/10.1016/S0003-2670(99)00160-9
Keywords: A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
DOI: 10.1016/S0003-2670(99)00160-9
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“Assessment of local analysis by Fourier transform laser microprobe mass spectrometry with external ion source”. van Roy W, Struyf H, Kennis P, Van Vaeck L, Van Grieken R, Andrle C, Microchimica acta 120, 121 (1995). http://doi.org/10.1007/BF01244426
Keywords: A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
DOI: 10.1007/BF01244426
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“Associations between ambient, personal, and indoor exposure to fine particulate matter constituents in Dutch and Finnish panels of cardiovascular patients”. Janssen NAH, Lanki T, Hoek G, Vallius M, de Hartog JJ, Van Grieken R, Pekkanen J, Brunekreef B, Occupational and environmental medicine 62, 868 (2005). http://doi.org/10.1136/OEM.2004.016618
Keywords: A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
DOI: 10.1136/OEM.2004.016618
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“Atmosferische fluxen van zware metalen naar de Noordzee”. Otten P, Injuk J, Rojas C, Van Grieken R, Het ingenieursblad 61, 41 (1992)
Keywords: A3 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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“Atmosferische fluxen van zware metalen naar de Noordzee”. Otten P, Injuk J, Rojas C, Van Grieken R, De ingenieur 5, 32 (1992)
Keywords: A3 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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“Atmospheric aerosol and stone conservation”. Van Grieken R, Delalieux F, Cardell Fernandez C page 111 (1999).
Keywords: H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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“Atmospheric aerosol particles: a review on sources, sinks and effects”. Hoornaert S, Van Grieken R, (2002)
Keywords: P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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“Atmospheric aerosols and deposition near historic buildings: chemistry, sources, interrelationships and relevance”. Van Grieken R, Torfs K, (1996)
Keywords: P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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“Atmospheric aerosols in the Asian part of the former Soviet Union”. Van Grieken R, Jaenicke R, Koutsenogii KP, Khodzher TV, Kulipanov GN, AIP conference proceedings
T2 –, 15th International Conference on Nucleation and Atmospheric Aerosols, (ICNAA), August 06-11, 2000, Univ. Missouri Rolla, Rolla, MO 534, 740 (2000)
Abstract: The paper presents the results of the study of atmospheric aerosols in the Siberian region. This research was focused on studying the chemical and biological characteristics of both natural and pollution aerosols in this vast territory of the Asian part of the former Soviet Union (FSU). The data received within the frame of this project formed the basis for the evaluation of the impact of these aerosols on the Arctic region and the global climate. The Asian part of FSU is of scientific interest in the context of environmental chemistry, air pollution and study of atmospheric aerosols, The specific relevance of aerosol research in Siberia is as follows. There are areas that are very remote from industrial or densely populated centres, In these circumstances, aerosol characterization contributes to the definition of global continental “background”) or “baseline” aerosol, i.e, the aerosol which should occur in natural circumstances and on which all pollution is superimposed. Recently, in the context of global and long-term climatic changes, baseline aerosols and long-range transport of particulate air pollutants have become a topic of much debate, This is because it has been thought that aerosols might compensate for the well-known greenhouse effect to a significant. In this context, more and more attention is being paid to long-range effects of continental aerosols on the polar regions. Research in Norway and Alaska showed that Western or Central Siberia may be a very important source of pollutants affecting the air composition in the Arctic region. Cities and regions in south Siberia are enormously polluted by heavy metals, the level of pollution being many times higher than in the Western world, thus the health of local population is seriously affected. In most cases, gigantic point sources are in the area, which is simple from the viewpoint of environmental chemistry and unambiguous results should be obtained easily. Atmospheric deposition is a possible cause of the existence of heavy metals in the southern part of Lake Baikal. in the northern part of the lake, the environment is unpolluted. However in the southern part of the lake is considerably threatened by pollution from Baikalsk wood-pulp mill and industrial enterprises of Irkutsk, Angarsk,
Keywords: P1 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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“Atmospheric aerosols in the Asian part of the former Soviet Union”. Van Grieken R, Jaenicke R, Koutsenogii KP, Khodzher TV, Kulipanov GN page 197 (1999).
Keywords: H1 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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“Atmospheric concentrations and deposition of heavy metals over the North Sea: a literature review”. Injuk J, Van Grieken R, Journal of atmospheric chemistry 20, 179 (1995). http://doi.org/10.1007/BF00696557
Keywords: A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
DOI: 10.1007/BF00696557
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“Atmospheric concentrations and size distributions of aircraft-sampled Cd, Cu, Pb and Zn over the Southern Bight of the North Sea”. Injuk J, Otten P, Laane R, Maenhaut W, Van Grieken R, Atmospheric environment : an international journal 26a, 2499 (1992). http://doi.org/10.1016/0960-1686(92)90102-Q
Keywords: A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
DOI: 10.1016/0960-1686(92)90102-Q
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“Atmospheric deposition and its impact on ecosystems, with particular reference to the Mid-East: proceedings of a symposium held in Tel-Aviv, Israel, on 5-6 June 2000, under the auspices of IUPAC”. Van Grieken R, Shevah Y page 170 p. (2002).
Keywords: ME3 Book as editor; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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“Atmospheric deposition as decay factor for the Demeter sanctuary ruins in the industrial atmosphere of Eleusis, Greece”. Moropoulou A, Bisbikou K, Torfs K, Van Grieken R, Environmental technology 19, 1039 (1998). http://doi.org/10.1080/09593331908616761
Keywords: A1 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
DOI: 10.1080/09593331908616761
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Bencs L, Horemans B, Van Grieken R, et al. (2012) Atmospheric deposition fluxes to the Belgian marine waters originating from ship emissions : SHIPFLUX : final report
Keywords: Minutes and reports; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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“Atmospheric deposition of heavy metals in the North Sea as studied by micro- and trace analysis”. Van Grieken R, de Bock L, Injuk J, van Malderen H page 284 (1994).
Keywords: H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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“Atmospheric inputs of heavy metals into the North Sea”. Injuk J, Van Grieken R, (1996)
Keywords: P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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“Atmospheric particles”. Harrison RM, Van Grieken RE page 610 p. (1998).
Keywords: ME3 Book as editor; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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“Atmospheric pollution at the Alhambra monument, Granada, Spain: a preventive conservation study”. Kontozova-Deutsch V, Horemans B, Cardell C, Van Grieken R, (2010)
Keywords: P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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“Automated energy-dispersive X-ray fluorescence analysis for diverse environmental samples”. Van Dyck P, Van Grieken R page 315 (1982).
Keywords: H3 Book chapter; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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“Automated EPXMA of individual environmental particles”. Van Grieken R, Artaxo P, Xhoffer C, (1992)
Keywords: P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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“Azimuthal and radial flow patterns of 1g-Geldart B-type particles in a gas-solid vortex reactor”. Gonzalez-Quiroga A, Kulkarni SR, Vandewalle L, Perreault P, Goel C, Heynderickx GJ, van Geem KM, Marin GB, Powder technology 354, 410 (2019). http://doi.org/10.1016/J.POWTEC.2019.06.015
Abstract: Processes requiring intensive interfacial momentum, mass and heat exchange between gases and particulate solids can be greatly enhanced by operating in a centrifugal field. This is realized in the Gas-Solid Vortex Reactor (GSVR) with centrifugal accelerations up to two orders of magnitude higher than the Earth's gravitational acceleration. Here, the flow patterns of two 1g-Geldart B-type particles are experimentally assessed, over the gas inlet velocity range 82–126 m s−1, in an 80 mm diameter and 15 mm height GSVR. The particles are monosized aluminum spheres of 0.5 mm diameter, and walnut shell in the sieve fraction 0.50–0.56 mm and aspect ratio 1.3 ± 0.2. Two dimensional Particle Image Velocimetry combined with Digital Image Analysis and pressure measurements revealed that periodic fluctuations in solids azimuthal and radial velocity between gas inlet slots are strongly related to the average solids azimuthal velocity and bed uniformity. Aluminum particles feature steeper changes in azimuthal velocity and more attenuated changes in radial velocity than walnut shell particles. Within the assessed gas inlet velocity range the solids bed of aluminum exhibits average azimuthal velocities and bed voidages 40–50% and ≈10% lower than those of walnut shell. The aerodynamic response time of the particles, i.e. ρsdp2/18μg, emerged as an important parameter to assess the influence of the carrier gas jet on the radial deflection of the particles and the interaction solids bed-outer wall. Too low aerodynamic response time relates to nonuniformity in bed voidage due to solids radial velocity fluctuations. Excessive aerodynamic response time indicates low solids azimuthal velocities due to solids bed-outer wall friction.
Keywords: A1 Journal article; Engineering sciences. Technology; Sustainable Energy, Air and Water Technology (DuEL)
DOI: 10.1016/J.POWTEC.2019.06.015
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“Background aerosol concentrations at the Namib-Atlantic interface”. Annegarn HJ, Van Grieken RE, Winchester JW, Sellschop JPF, von Blottnitz F, (1979)
Keywords: P3 Proceeding; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation)
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