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Author |
Verbueken, A.H.; Bruynseels, F.J.; Van Grieken, R.E. |
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Title |
Laser microprobe mass analysis : a review of applications in the life sciences |
Type |
A3 Journal article |
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Year |
1985 |
Publication |
Biomedical mass spectrometry |
Abbreviated Journal |
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Volume |
12 |
Issue |
9 |
Pages |
438-463 |
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Keywords |
A3 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation) |
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Abstract |
The characteristics and analytical utility of laser microprobe mass analysis (LAMMA) are described and evaluated, and a short history of this recent microanalytical technique is presented. A review of the areas of application of LAMMA and related laser microprobes is presented with special emphasis on applications in the life sciences. |
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Publication Date |
2005-05-31 |
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Edition |
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ISSN |
0306-042x |
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UA library record |
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Open Access |
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no |
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Call Number |
UA @ admin @ c:irua:116722 |
Serial |
8153 |
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Author |
Verbueken, A.H.; Van Grieken, R.E.; Paulus, G.J.; Verpooten, G.A.; de Broe, M.E. |
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Title |
Laser microprobe mass spectrometry of platinum in dog kidney after cisplatin adminstration |
Type |
A3 Journal article |
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Year |
1984 |
Publication |
Biomedical mass spectrometry |
Abbreviated Journal |
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Volume |
11 |
Issue |
4 |
Pages |
159-163 |
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Keywords |
A3 Journal article; AXES (Antwerp X-ray Analysis, Electrochemistry and Speciation); Laboratory Experimental Medicine and Pediatrics (LEMP) |
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Abstract |
By means of laser microprobe mass analysis (LAMMA) platinum was detected in the renal proximal tubular cells of a dog that had been intravenously adminstered the antitumor drug cisplatin (5 mg per kg body weight). No definite subcellular localization of the heavy metal was obtained. Sample prparation and analytical features are examined to increase spatial resolution of analysis while maintaining sufficient detection efficiency. The LAMMA method is destructive, but the amount and type of evaporated material can readily be determined when using LAMMA in combination with transmission electron microscopy. Instrumental optimization and standardization of mass signals is possible by using platinum-loaded, ion chelating resin beads embedded and sectioned with the tissue. |
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Publication Date |
2005-05-28 |
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Series Issue |
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Edition |
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ISSN |
0306-042x |
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Additional Links |
UA library record |
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Times cited |
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Open Access |
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Notes |
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no |
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Call Number |
UA @ admin @ c:irua:116712 |
Serial |
8165 |
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Permanent link to this record |