“NanoMIPs-based electrochemical sensors for selective detection of amphetamine”. Truta F, Cruz AG, Tertis M, Zaleski C, Adamu G, Allcock NS, Suciu M, Stefan M-G, Kiss B, Piletska E, De Wael K, Piletsky SA, Cristea C, Microchemical journal 191, 108821 (2023). http://doi.org/10.1016/J.MICROC.2023.108821
Abstract: A highly sensitive and portable electrochemical sensor based on molecularly imprinted nanoparticles (nanoMIPs) was developed. NanoMIPs were computationally designed for specific recognition of amphetamine, and then synthetized using solid phase synthesis. NanoMIPs were immobilized onto screen-printed carbon electrodes using a composite film comprising chitosan, nanoMIPs, and graphene oxide.Ferrocenylmethyl methacrylate was incorporated in nanoMIPs allowing electrochemical detection. The signal recorded for the electrochemical oxidation of ferrocene has proven to be dependent on the presence of amphetamine interacting with nanMIPs. The sensor was tested successfully with street samples, with high sensitivity and satisfactory recoveries (from 100.9% to 107.6%). These results were validated with UPL-MS/MS. The present technology is suitable for forensic applications in selective determination of amphetamine in street samples.
Keywords: A1 Journal article; Antwerp Electrochemical and Analytical Sciences Lab (A-Sense Lab)
Impact Factor: 4.8
DOI: 10.1016/J.MICROC.2023.108821
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